Esplenectomía en púrpura trombocitopénica idiopática.

Translated title of the contribution: Splenectomy in idiopathic thrombocytopenic purpura

M. F. Herrera Hernández, X. López-Karpovitch, E. Rivero Sigarroa, Alberto M Odor, L. de la Garza Villaseñor

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Between January 1976 and December 1987, 44 patients with idiopathic thrombocytopenic purpura were submitted to splenectomy. This study analyzes the results of treatment and the usefulness of several prognostic markers. There were 38 female patients and six males with a median age of 28.5 years (range 11 to 66 years). Forty two out of 44 patients received preoperative steroids. Seventy five percent achieved a satisfactory response to this treatment but 31 relapsed (in eight recurrence was observed when the steroid dose was tapered). Eleven patients persisted symptomatic notwithstanding medical treatment. In two cases splenectomy was performed as an emergency procedure, and in one patient who was already in remission with previous steroid treatment, splenectomy was performed for other medical reasons. Operative mortality rate was 4 percent, and five patients developed postoperative complications (three had pneumonia, one pulmonary thromboembolism and one would infection). Eighty four percent of the patients were free of disease at one year followup survival at 10 year period was 80 percent. No correlation was found between age, duration of symptoms, previous response to steroids or time-period of medical treatment with the results obtained with splenectomy.

Original languageSpanish
Pages (from-to)14-17
Number of pages4
JournalRevista de Investigacion Clinica
Volume42
Issue number1
StatePublished - Jan 1990
Externally publishedYes

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Idiopathic Thrombocytopenic Purpura
Splenectomy
Steroids
Therapeutics
Pulmonary Embolism
Pneumonia
Emergencies
Recurrence
Survival
Mortality
Infection

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Herrera Hernández, M. F., López-Karpovitch, X., Rivero Sigarroa, E., Odor, A. M., & de la Garza Villaseñor, L. (1990). Esplenectomía en púrpura trombocitopénica idiopática. Revista de Investigacion Clinica, 42(1), 14-17.

Esplenectomía en púrpura trombocitopénica idiopática. / Herrera Hernández, M. F.; López-Karpovitch, X.; Rivero Sigarroa, E.; Odor, Alberto M; de la Garza Villaseñor, L.

In: Revista de Investigacion Clinica, Vol. 42, No. 1, 01.1990, p. 14-17.

Research output: Contribution to journalArticle

Herrera Hernández, MF, López-Karpovitch, X, Rivero Sigarroa, E, Odor, AM & de la Garza Villaseñor, L 1990, 'Esplenectomía en púrpura trombocitopénica idiopática.', Revista de Investigacion Clinica, vol. 42, no. 1, pp. 14-17.
Herrera Hernández MF, López-Karpovitch X, Rivero Sigarroa E, Odor AM, de la Garza Villaseñor L. Esplenectomía en púrpura trombocitopénica idiopática. Revista de Investigacion Clinica. 1990 Jan;42(1):14-17.
Herrera Hernández, M. F. ; López-Karpovitch, X. ; Rivero Sigarroa, E. ; Odor, Alberto M ; de la Garza Villaseñor, L. / Esplenectomía en púrpura trombocitopénica idiopática. In: Revista de Investigacion Clinica. 1990 ; Vol. 42, No. 1. pp. 14-17.
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