Spiromastigoides asexualis: Phylogenetic analysis and evaluation as a cause of false-positive blastomyces DNA probe test results

Minh Vu H. Nguyen, Nathan P. Wiederhold, Connie Cañete-Gibas, Carmita Sanders, George R. Thompson

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

This is the first case of Spiromastigoides asexualis human infection, and it notably gave a false-positive Blastomyces DNA probe laboratory result. We further investigated other Spiromastigoides isolates as a cause of false-positive testing results, their phylogenetic relationship, and their susceptibility profiles to clinically available antifungal agents. Other S. asexualis isolates also resulted in positive Blastomyces DNA probe results, while Spiromastigoides species other than S. asexualis did not.

Original languageEnglish (US)
Article numbere01325-20
JournalJournal of clinical microbiology
Volume58
Issue number12
DOIs
StatePublished - Dec 2020

Keywords

  • Blastomyces
  • Blastomycosis
  • DNA probe
  • False-positive
  • Fungal
  • Fungus
  • Mold
  • Novel
  • Phylogenetic
  • Phylogenetics
  • Spiromastigoides

ASJC Scopus subject areas

  • Microbiology (medical)

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