Spectroscopic imaging of bladder cancer

Stavros G. Demos, Regina F Gandour-Edwards, Rajen Ramsamooj, Ralph W deVere White

Research output: Chapter in Book/Report/Conference proceedingConference contribution


The feasibility of developing bladder cancer detection methods using intrinsic tissue optical properties is the focus of this investigation. In vitro experiments have been performed using polarized elastic light scattering in combination with tissue autofluorescence in the NIR spectral region under laser excitation in the green and red spectral regions. The experimental results obtained from a set of tissue specimens from 25 patients reveal the presence of optical fingerprint characteristics suitable for cancer detection with high contrast and accuracy. These photonic methods are compatible with existing endoscopic imaging modalities which make them suitable for in-vivo application.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
EditorsL.S. Bass, N Kollias, R.S. Malek, A Katzir, U.K. Shah, B.J.F. Wong, E.A. Trowers, T.A. Woodward, W.T.W. de Riese, D.S. Robinson, H-D Reidenbach, K.D. Paulsen, K.W. Gregory
Number of pages4
StatePublished - 2003
EventLasers in Surgery: Advanced Characterization, Therapeutics, and Systems XIII - San Jose,CA, United States
Duration: Jan 25 2003Jan 26 2003


OtherLasers in Surgery: Advanced Characterization, Therapeutics, and Systems XIII
Country/TerritoryUnited States
CitySan Jose,CA


  • Backscattering
  • Polarization
  • Tissue autofluorescence
  • Tissue Imaging

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Condensed Matter Physics


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