Abstract
The feasibility of developing bladder cancer detection methods using intrinsic tissue optical properties is the focus of this investigation. In vitro experiments have been performed using polarized elastic light scattering in combination with tissue autofluorescence in the NIR spectral region under laser excitation in the green and red spectral regions. The experimental results obtained from a set of tissue specimens from 25 patients reveal the presence of optical fingerprint characteristics suitable for cancer detection with high contrast and accuracy. These photonic methods are compatible with existing endoscopic imaging modalities which make them suitable for in-vivo application.
Original language | English (US) |
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Title of host publication | Proceedings of SPIE - The International Society for Optical Engineering |
Editors | L.S. Bass, N Kollias, R.S. Malek, A Katzir, U.K. Shah, B.J.F. Wong, E.A. Trowers, T.A. Woodward, W.T.W. de Riese, D.S. Robinson, H-D Reidenbach, K.D. Paulsen, K.W. Gregory |
Pages | 125-128 |
Number of pages | 4 |
Volume | 4949 |
DOIs | |
State | Published - 2003 |
Event | Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems XIII - San Jose,CA, United States Duration: Jan 25 2003 → Jan 26 2003 |
Other
Other | Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems XIII |
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Country/Territory | United States |
City | San Jose,CA |
Period | 1/25/03 → 1/26/03 |
Keywords
- Backscattering
- Polarization
- Tissue autofluorescence
- Tissue Imaging
ASJC Scopus subject areas
- Electrical and Electronic Engineering
- Condensed Matter Physics