Spectral imaging in biomedicine: A selective overview

Richard M Levenson, Elliot S. Wachmn, Wenhua Niu, Daniel L. Farkas

Research output: Chapter in Book/Report/Conference proceedingConference contribution

25 Scopus citations

Abstract

We present a survey of spectral imaging for biological and medical applications. Brief philosophical and historical considerations are followed by an overview of the reasons for and modalities of achieving the fertile confluence of spectroscopy and imaging. Methods of wavelength selection at both the excitation and detection ends of an imaging system are listed and critically evaluated. A number of biological and medical applications of spectral imaging are discussed, highlighting microscopy and including our own work. We emphasize that the outlook for this research area critically depends on the further development of all component technologies, from reagents and optics to electronics and software.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
EditorsM.R. Descour, S.S. Shen
Pages300-312
Number of pages13
Volume3438
DOIs
StatePublished - 1998
Externally publishedYes
EventImaging Spectrometry IV - San Diego, United States
Duration: Jul 20 1998Jul 21 1998

Other

OtherImaging Spectrometry IV
CountryUnited States
CitySan Diego
Period7/20/987/21/98

Keywords

  • Bio-medical
  • Classification
  • Fluoresc ence
  • Imaging
  • Immunohistochemistry
  • Instrumentation
  • Multiparameter
  • Pathology
  • Segmentation
  • Spectral

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Condensed Matter Physics

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  • Cite this

    Levenson, R. M., Wachmn, E. S., Niu, W., & Farkas, D. L. (1998). Spectral imaging in biomedicine: A selective overview. In M. R. Descour, & S. S. Shen (Eds.), Proceedings of SPIE - The International Society for Optical Engineering (Vol. 3438, pp. 300-312) https://doi.org/10.1117/12.328111