Speciation of Arsenic Oxides Using Laser Desorption/Ionization Time-of-Flight Mass Spectrometry

Todd M. Allen, Dawit Z. Bezabeh, Catherine H. Smith, Eileen M. McCauley, A. Daniel Jones, Daniel P Y Chang, Ian M. Kennedy, Peter B. Kelly

Research output: Contribution to journalArticle

19 Scopus citations


Positive and negative ion mass spectra of arsenic trioxide (As2O3) and arsenic pentaoxide (As2O5) have been obtained by single-step laser desorption/ionization time-of-flight mass spectrometry. Pulsed UV radiation at 266 nm was used for the simultaneous desorption and ionization of the solid sample. High-mass cluster ions that are unique to the oxidation state of each oxide sample appear in the negative ion mass spectra. The As2O3 produces As3O5 -, while the As2O5 yields As3O8 -. The formation of unique negative cluster ions presents the capability for arsenic oxidation state speciation by laser desorption/ ionization mass spectrometry. The ability of time-of-flight mass spectrometry to examine the relative amounts of each arsenic oxide present in a series of mixtures is discussed. Application of our speciation technique to a model incinerator sample is demonstrated.

Original languageEnglish (US)
Pages (from-to)4052-4059
Number of pages8
JournalAnalytical Chemistry
Issue number22
Publication statusPublished - Nov 15 1996


ASJC Scopus subject areas

  • Analytical Chemistry

Cite this

Allen, T. M., Bezabeh, D. Z., Smith, C. H., McCauley, E. M., Jones, A. D., Chang, D. P. Y., ... Kelly, P. B. (1996). Speciation of Arsenic Oxides Using Laser Desorption/Ionization Time-of-Flight Mass Spectrometry. Analytical Chemistry, 68(22), 4052-4059.