Spatial and temporal control of hyperthermia using real time thermal strain imaging with motion compensation

Josquin Foiret, Katherine W. Ferrara

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations

Abstract

Ultrasound mild hyperthermia has been employed to induce physiological changes that can directly treat cancer and enhance local drug delivery. For mild hyperthermia, temperature monitoring is essential to avoid undesirable biological effects. In previous work by our group, control of mild hyperthermia was achieved using a proportional-integral-derivative (PID) controller based on thermocouple measurements [1]. Despite good temporal control of heating, this method was limited by the fact that temperature was measured only at the thermocouple position. Ultrasound thermometry techniques based on exploiting the thermal dependence of the longitudinal wave speed can be extended to create thermal maps and allow accurate monitoring of temperature with good spatial resolution. However, in vivo applications of this technique have not been fully developed due to the high sensitivity to tissue motion. Here, we address translational and compressional motion compensation and demonstrate effective thermometry in the presence of physiological-scale motion.

Original languageEnglish (US)
Title of host publicationIEEE International Ultrasonics Symposium, IUS
PublisherIEEE Computer Society
Pages2133-2136
Number of pages4
ISBN (Print)9781479970490
DOIs
StatePublished - Oct 20 2014
Event2014 IEEE International Ultrasonics Symposium, IUS 2014 - Chicago, United States
Duration: Sep 3 2014Sep 6 2014

Other

Other2014 IEEE International Ultrasonics Symposium, IUS 2014
CountryUnited States
CityChicago
Period9/3/149/6/14

    Fingerprint

Keywords

  • motion compensation
  • PID control
  • thermometry

ASJC Scopus subject areas

  • Acoustics and Ultrasonics

Cite this

Foiret, J., & Ferrara, K. W. (2014). Spatial and temporal control of hyperthermia using real time thermal strain imaging with motion compensation. In IEEE International Ultrasonics Symposium, IUS (pp. 2133-2136). [6932333] IEEE Computer Society. https://doi.org/10.1109/ULTSYM.2014.0531