Abstract
Background: We have previously shown that healthy male volunteers after oral lactulose develop significant abdominal bloating, excessive flatus passage and increased breath hydrogen. Objective: The aim of this study was to measure breath hydrogen, abdominal bloating and flatus passage after oral sorbitol and to compare these parameters with those produced by lactulose. Materials and Methods: The same normal volunteers who had participated in the lactulose study also were used in this study. After oral sorbitol, bloating score, number of flatus passage and breath hydrogen over a period of 8 hours was measured. These parameters were compared with those which had been obtained after lactulose. Results: These male healthy volunteers after oral sorbitol produced breath hydrogen, had abdominal bloating and passed flatus similar to that produced after lactulose. Conclusion: Gastrointestinal symptoms produced by some foods and fruits in otherwise healthy persons may be due to the sorbitol content of those foods. The manufacturers should clearly state the amount of sorbitol in such foods.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 31-33 |
| Number of pages | 3 |
| Journal | International Medical Journal |
| Volume | 14 |
| Issue number | 1 |
| State | Published - Mar 2007 |
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Keywords
- Bloating
- Breath hydrogen
- Flatus
- Lactulose
- Sorbitol
ASJC Scopus subject areas
- Medicine(all)
Cite this
Sorbitol induced breath hydrogen in healthy volunteers. / Mann, Nirmal S; Cheung, Eddie C.
In: International Medical Journal, Vol. 14, No. 1, 03.2007, p. 31-33.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Sorbitol induced breath hydrogen in healthy volunteers
AU - Mann, Nirmal S
AU - Cheung, Eddie C.
PY - 2007/3
Y1 - 2007/3
N2 - Background: We have previously shown that healthy male volunteers after oral lactulose develop significant abdominal bloating, excessive flatus passage and increased breath hydrogen. Objective: The aim of this study was to measure breath hydrogen, abdominal bloating and flatus passage after oral sorbitol and to compare these parameters with those produced by lactulose. Materials and Methods: The same normal volunteers who had participated in the lactulose study also were used in this study. After oral sorbitol, bloating score, number of flatus passage and breath hydrogen over a period of 8 hours was measured. These parameters were compared with those which had been obtained after lactulose. Results: These male healthy volunteers after oral sorbitol produced breath hydrogen, had abdominal bloating and passed flatus similar to that produced after lactulose. Conclusion: Gastrointestinal symptoms produced by some foods and fruits in otherwise healthy persons may be due to the sorbitol content of those foods. The manufacturers should clearly state the amount of sorbitol in such foods.
AB - Background: We have previously shown that healthy male volunteers after oral lactulose develop significant abdominal bloating, excessive flatus passage and increased breath hydrogen. Objective: The aim of this study was to measure breath hydrogen, abdominal bloating and flatus passage after oral sorbitol and to compare these parameters with those produced by lactulose. Materials and Methods: The same normal volunteers who had participated in the lactulose study also were used in this study. After oral sorbitol, bloating score, number of flatus passage and breath hydrogen over a period of 8 hours was measured. These parameters were compared with those which had been obtained after lactulose. Results: These male healthy volunteers after oral sorbitol produced breath hydrogen, had abdominal bloating and passed flatus similar to that produced after lactulose. Conclusion: Gastrointestinal symptoms produced by some foods and fruits in otherwise healthy persons may be due to the sorbitol content of those foods. The manufacturers should clearly state the amount of sorbitol in such foods.
KW - Bloating
KW - Breath hydrogen
KW - Flatus
KW - Lactulose
KW - Sorbitol
UR - http://www.scopus.com/inward/record.url?scp=34047249625&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=34047249625&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:34047249625
VL - 14
SP - 31
EP - 33
JO - International Medical Journal
JF - International Medical Journal
SN - 1341-2051
IS - 1
ER -