Sonothrombolysis with phospholipid-coated perfluoropropane microbubbles

Evan Unger; Terry O. Matsunaga; Reena Zutshi; Rachel Labell; Thomas R. Porter; John Lof; Feng Xie; Katherine Ferrara; Paul Dayton; Susannah Bloch

doi:10.1063/1.1901599

Sonothrombolysis with phospholipid-coated perfluoropropane microbubbles

Evan Unger, Terry O. Matsunaga, Reena Zutshi, Rachel Labell, Thomas R. Porter, John Lof, Feng Xie, Katherine Ferrara, Paul Dayton, Susannah Bloch

Biomedical Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

2 Scopus citations

Abstract

Compared to other modalities that might be employed for molecular imaging, ultrasound has some unique features. It is portable; highly adapted to the surgical environment; can be used for cavitation, heating, and tissue ablation; and is exquisitely sensitive to microbubbles. Using microbubbles as a contrast agent, ultrasound imaging can detect a single microbubble. Ultrasound in concert with bubbles can be used in NanoInvasive™ therapy and drug delivery. An example of NanoInvasive therapy is sonothrombolysis with microbubbles, or SonoLysis™.

Original language	English (US)
Title of host publication	AIP Conference Proceedings
Pages	58-61
Number of pages	4
Volume	754
DOIs	https://doi.org/10.1063/1.1901599
State	Published - Mar 28 2005
Event	4th International Symposium on Therapeutic Ultrasound - Kyoto, Japan Duration: Sep 18 2004 → Sep 20 2004

Other

Other	4th International Symposium on Therapeutic Ultrasound
Country	Japan
City	Kyoto
Period	9/18/04 → 9/20/04

ASJC Scopus subject areas

Physics and Astronomy(all)

Access to Document

10.1063/1.1901599

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Sonothrombolysis with phospholipid-coated perfluoropropane microbubbles. / Unger, Evan; Matsunaga, Terry O.; Zutshi, Reena; Labell, Rachel; Porter, Thomas R.; Lof, John; Xie, Feng; Ferrara, Katherine; Dayton, Paul; Bloch, Susannah.

AIP Conference Proceedings. Vol. 754 2005. p. 58-61.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

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abstract = "Compared to other modalities that might be employed for molecular imaging, ultrasound has some unique features. It is portable; highly adapted to the surgical environment; can be used for cavitation, heating, and tissue ablation; and is exquisitely sensitive to microbubbles. Using microbubbles as a contrast agent, ultrasound imaging can detect a single microbubble. Ultrasound in concert with bubbles can be used in NanoInvasive{\texttrademark} therapy and drug delivery. An example of NanoInvasive therapy is sonothrombolysis with microbubbles, or SonoLysis{\texttrademark}.",

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AU - Lof, John

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AU - Ferrara, Katherine

AU - Dayton, Paul

AU - Bloch, Susannah

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