Solution phase synthesis of (1→5)-amide linked sugar amino acid dimers derived from sialic acids

Jacquelyn Gervay-Hague, Terrence M. Flaherty, Can Nguyen

Research output: Contribution to journalArticle

44 Scopus citations

Abstract

Carboxy-protected amino derivatives and amino-protected carboxy derivatives of three different C-2 analogs as well as a 2,3-dehydro NeuAc were prepared. These monomers were coupled in solution using BOP activation of the carboxy terminus to form (1→5)-amide linked dimers of sialyl amino acid derivatives.

Original languageEnglish (US)
Pages (from-to)1493-1496
Number of pages4
JournalTetrahedron Letters
Volume38
Issue number9
DOIs
StatePublished - Mar 3 1997
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

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