Solution-Phase Hexasaccharide Synthesis Using Glucosyl Iodides

Research output: Contribution to journalArticle

61 Citations (Scopus)

Abstract

(Equation Presented) Oligosaccharides composed of 1,6-glucosyl residues have been prepared from glucosyl iodides. The reactions are highly stereoselective, giving the α-glycosides as the only isolated products in yields ranging from 84% to 94%. Oligomer synthesis can take place in an iterative 1 + 1 + 1 fashion or in a convergent manner where dimer iodides serve as donors for higher order acceptors.

Original languageEnglish (US)
Pages (from-to)2039-2042
Number of pages4
JournalOrganic Letters
Volume4
Issue number12
DOIs
StatePublished - Jun 13 2002

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Iodides
iodides
glucosides
synthesis
Glycosides
Oligosaccharides
oligomers
Oligomers
Dimers
dimers
products

ASJC Scopus subject areas

  • Molecular Medicine

Cite this

Solution-Phase Hexasaccharide Synthesis Using Glucosyl Iodides. / Lam, Son N.; Gervay-Hague, Jacquelyn.

In: Organic Letters, Vol. 4, No. 12, 13.06.2002, p. 2039-2042.

Research output: Contribution to journalArticle

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