Abstract
(Equation Presented) Oligosaccharides composed of 1,6-glucosyl residues have been prepared from glucosyl iodides. The reactions are highly stereoselective, giving the α-glycosides as the only isolated products in yields ranging from 84% to 94%. Oligomer synthesis can take place in an iterative 1 + 1 + 1 fashion or in a convergent manner where dimer iodides serve as donors for higher order acceptors.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 2039-2042 |
| Number of pages | 4 |
| Journal | Organic Letters |
| Volume | 4 |
| Issue number | 12 |
| DOIs | |
| State | Published - Jun 13 2002 |
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ASJC Scopus subject areas
- Molecular Medicine
Cite this
Solution-Phase Hexasaccharide Synthesis Using Glucosyl Iodides. / Lam, Son N.; Gervay-Hague, Jacquelyn.
In: Organic Letters, Vol. 4, No. 12, 13.06.2002, p. 2039-2042.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Solution-Phase Hexasaccharide Synthesis Using Glucosyl Iodides
AU - Lam, Son N.
AU - Gervay-Hague, Jacquelyn
PY - 2002/6/13
Y1 - 2002/6/13
N2 - (Equation Presented) Oligosaccharides composed of 1,6-glucosyl residues have been prepared from glucosyl iodides. The reactions are highly stereoselective, giving the α-glycosides as the only isolated products in yields ranging from 84% to 94%. Oligomer synthesis can take place in an iterative 1 + 1 + 1 fashion or in a convergent manner where dimer iodides serve as donors for higher order acceptors.
AB - (Equation Presented) Oligosaccharides composed of 1,6-glucosyl residues have been prepared from glucosyl iodides. The reactions are highly stereoselective, giving the α-glycosides as the only isolated products in yields ranging from 84% to 94%. Oligomer synthesis can take place in an iterative 1 + 1 + 1 fashion or in a convergent manner where dimer iodides serve as donors for higher order acceptors.
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U2 - 10.1021/ol025887d
DO - 10.1021/ol025887d
M3 - Article
VL - 4
SP - 2039
EP - 2042
JO - Organic Letters
JF - Organic Letters
SN - 1523-7060
IS - 12
ER -