Soluble mammalian epoxide hydratase: Action on juvenile hormone and other terpenoid epoxides

Bruce D. Hammock, Sarjeet S. Gill, Vassiliki Stamoudis, Lawrence I. Gilbert

Research output: Contribution to journalArticle

42 Citations (Scopus)

Abstract

1. 1. A soluble epoxide hydratase from mouse liver or kidney converts juvenile hormone and two epoxide containing juvenoids to their respective diols faster than the microsomal epoxide hydratases. 2. 2. The soluble enzyme hydrates the two trisubstituted epoxides much faster than the tetrasubstituted epoxide. 3. 3. Analysis by gel filtration indicates an approximate mol. wt of 150,000 for the liver enzyme while isoelectric focusing indicates a pI of 4·9.

Original languageEnglish (US)
Pages (from-to)263-265
Number of pages3
JournalComparative Biochemistry and Physiology -- Part B: Biochemistry and
Volume53
Issue number2
DOIs
StatePublished - 1976
Externally publishedYes

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Epoxide Hydrolases
Juvenile Hormones
Epoxy Compounds
Terpenes
Liver
Isoelectric Focusing
Enzymes
Hydrates
Gel Chromatography
Gels
Kidney

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Soluble mammalian epoxide hydratase : Action on juvenile hormone and other terpenoid epoxides. / Hammock, Bruce D.; Gill, Sarjeet S.; Stamoudis, Vassiliki; Gilbert, Lawrence I.

In: Comparative Biochemistry and Physiology -- Part B: Biochemistry and, Vol. 53, No. 2, 1976, p. 263-265.

Research output: Contribution to journalArticle

Hammock, Bruce D. ; Gill, Sarjeet S. ; Stamoudis, Vassiliki ; Gilbert, Lawrence I. / Soluble mammalian epoxide hydratase : Action on juvenile hormone and other terpenoid epoxides. In: Comparative Biochemistry and Physiology -- Part B: Biochemistry and. 1976 ; Vol. 53, No. 2. pp. 263-265.
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