Solid phase synthesis of [18F]labelled peptides for positron emission tomography

Julie Sutcliffe, Michael J. O'Doherty, Sukhvinder S. Bansal

Research output: Contribution to journalArticlepeer-review

29 Scopus citations


A strategy for the solid phase synthesis of [18F]labelled peptides has been developed. The peptides were prepared on solid support and acylated with 4-[18F]fluorobenzoic acid using HATU within 3 min and the labelled peptide was released from the solid support within 7 min. The [18F]labelled peptides were produced in good purity with a specific activity of 20-25 GBq/μmol. (C) 2000 Elsevier Science Ltd. All rights reserved.

Original languageEnglish (US)
Pages (from-to)1501-1503
Number of pages3
JournalBioorganic and Medicinal Chemistry Letters
Issue number14
StatePublished - Jul 17 2000
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Organic Chemistry
  • Drug Discovery
  • Pharmaceutical Science


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