Solid and papillary neoplasm of the pancreas: Radiological-pathological study of five cases and review of the literature

Paul R Dong, D. S K Lu, F. Degregario, S. C. Fell, A. Au, B. M. Kadell

Research output: Contribution to journalArticle

61 Scopus citations

Abstract

Objective: To present five cases of the rare solid and papillary neoplasm of the pancreas with pathological correlation and review of the literature. Patients and methods: Five patients (all female, two Caucasian, one Philipino and two Hispanic) with solid and papillary neoplasm of the pancreas were reviewed. Four patients were under 28 years of age but one patient was 44 years old at presentation. Review consisted of imaging (CT in all and ultrasound in three patients), gross pathological and histological appearance (5/5 specimens), immunohistochemistry (4/5 specimens) and clinical follow-up. Results: All five tumours were successfully resected without recurrence. All tumours were well-encapsulated but showed a wide spectrum of solid peripheral tumour with central cystic degeneration on imaging. Cystic spaces corresponded to haemorrhagic necrosis on histology. One tumour showed rim calcification. Immunohistological staining showed variable expression of both exocrine and endocrine markers. Conclusion: Although non-specific, solid and papillary neoplasm of the pancreas is characteristically a benign, well-encapsulated solid tumor with varying degree of central necrosis in young female patients. No racial predilection was demonstrated in this small series.

Original languageEnglish (US)
Pages (from-to)702-705
Number of pages4
JournalBrain and Language
Volume51
Issue number10
StatePublished - 1996

ASJC Scopus subject areas

  • Language and Linguistics
  • Neuroscience(all)
  • Experimental and Cognitive Psychology
  • Neuropsychology and Physiological Psychology

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