Society of Urologic Oncology position statement: Redefining the management of hormone-refractory prostate carcinoma

Sam S. Chang, Mitchell C. Benson, Steven C. Campbell, Juanita Crook, Robert Dreicer, Christopher P Evans, M. Craig Hall, Celestia Higano, W. Kevin Kelly, Oliver Sartor, Joseph A. Smith

Research output: Contribution to journalArticle

28 Scopus citations

Abstract

Because patients with hormone-refractory prostate carcinoma are a very diverse group, management of these patients represents a unique challenge. Despite much research, to the authors' knowledge few studies published to date have provided definitive treatment answers. The Society of Urologic Oncology (SUO) convened a multidisciplinary panel of urologists, oncologists, and radiation oncologists to develop a treatment algorithm for patients with hormone-refractory prostate carcinoma. The resulting treatment outline was based on a review of the literature review and on the expert opinions of the panelists. The current article provided a logical progression of treatment choices that included hormonal manipulations, chemotherapeutic options, and adjunctive therapies. Future clinical trials and therapies were also discussed by the authors. Management strategies should be targeted toward the individual patient. Although significant progress has been made in understanding and treating hormone-refractory prostate carcinoma, earlier interventions would be ideal and better therapeutic approaches to prolong survival are necessary.

Original languageEnglish (US)
Pages (from-to)11-21
Number of pages11
JournalCancer
Volume103
Issue number1
DOIs
StatePublished - Jan 1 2005

Keywords

  • Androgen deprivation
  • Hormone refractory
  • Prostate carcinoma
  • Therapy

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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    Chang, S. S., Benson, M. C., Campbell, S. C., Crook, J., Dreicer, R., Evans, C. P., Hall, M. C., Higano, C., Kelly, W. K., Sartor, O., & Smith, J. A. (2005). Society of Urologic Oncology position statement: Redefining the management of hormone-refractory prostate carcinoma. Cancer, 103(1), 11-21. https://doi.org/10.1002/cncr.20726