Abstract
Social transmission of food preference (STFP) is a test of olfactory memory that can be used in mice. Confounds in STFP that can lead to misinterpretation of an STFP deficit as a memory impairment include changes in social interaction and olfaction. The issue of changes in social interaction was addressed by evaluating an observer-centric and a demonstrator-centric method for scoring the interaction phase of STFP in mice. The demonstrator-centric method was applied to a line of STFP-impaired, galaninoverexpressing transgenic (GAL-tg). GAL-tg mice were impaired in STFP without deficits in social interaction. In tests of olfactory ability, GAL-tg mice were unimpaired on buried-food and habituationdishabituation tasks. The current studies describe an expanded method for using STFP in mice and confirm a deficit in olfactory memory in GAL-tg mice.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 21-31 |
| Number of pages | 11 |
| Journal | Behavioral Neuroscience |
| Volume | 117 |
| Issue number | 1 |
| DOIs | |
| State | Published - Feb 2003 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Behavioral Neuroscience
- Clinical Psychology
Cite this
Social transmission of food preference in mice : Methodology and application to galanin-overexpressing transgenic mice. / Wrenn, Craige C.; Harris, Ashley P.; Saavedra, Maria C.; Crawley, Jacqueline.
In: Behavioral Neuroscience, Vol. 117, No. 1, 02.2003, p. 21-31.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Social transmission of food preference in mice
T2 - Methodology and application to galanin-overexpressing transgenic mice
AU - Wrenn, Craige C.
AU - Harris, Ashley P.
AU - Saavedra, Maria C.
AU - Crawley, Jacqueline
PY - 2003/2
Y1 - 2003/2
N2 - Social transmission of food preference (STFP) is a test of olfactory memory that can be used in mice. Confounds in STFP that can lead to misinterpretation of an STFP deficit as a memory impairment include changes in social interaction and olfaction. The issue of changes in social interaction was addressed by evaluating an observer-centric and a demonstrator-centric method for scoring the interaction phase of STFP in mice. The demonstrator-centric method was applied to a line of STFP-impaired, galaninoverexpressing transgenic (GAL-tg). GAL-tg mice were impaired in STFP without deficits in social interaction. In tests of olfactory ability, GAL-tg mice were unimpaired on buried-food and habituationdishabituation tasks. The current studies describe an expanded method for using STFP in mice and confirm a deficit in olfactory memory in GAL-tg mice.
AB - Social transmission of food preference (STFP) is a test of olfactory memory that can be used in mice. Confounds in STFP that can lead to misinterpretation of an STFP deficit as a memory impairment include changes in social interaction and olfaction. The issue of changes in social interaction was addressed by evaluating an observer-centric and a demonstrator-centric method for scoring the interaction phase of STFP in mice. The demonstrator-centric method was applied to a line of STFP-impaired, galaninoverexpressing transgenic (GAL-tg). GAL-tg mice were impaired in STFP without deficits in social interaction. In tests of olfactory ability, GAL-tg mice were unimpaired on buried-food and habituationdishabituation tasks. The current studies describe an expanded method for using STFP in mice and confirm a deficit in olfactory memory in GAL-tg mice.
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U2 - 10.1037/0735-7044.117.1.21
DO - 10.1037/0735-7044.117.1.21
M3 - Article
C2 - 12619904
AN - SCOPUS:0037311762
VL - 117
SP - 21
EP - 31
JO - Behavioral Neuroscience
JF - Behavioral Neuroscience
SN - 0735-7044
IS - 1
ER -