Social transmission of food preference in mice: Methodology and application to galanin-overexpressing transgenic mice

Craige C. Wrenn, Ashley P. Harris, Maria C. Saavedra, Jacqueline Crawley

Research output: Contribution to journalArticle

87 Citations (Scopus)

Abstract

Social transmission of food preference (STFP) is a test of olfactory memory that can be used in mice. Confounds in STFP that can lead to misinterpretation of an STFP deficit as a memory impairment include changes in social interaction and olfaction. The issue of changes in social interaction was addressed by evaluating an observer-centric and a demonstrator-centric method for scoring the interaction phase of STFP in mice. The demonstrator-centric method was applied to a line of STFP-impaired, galaninoverexpressing transgenic (GAL-tg). GAL-tg mice were impaired in STFP without deficits in social interaction. In tests of olfactory ability, GAL-tg mice were unimpaired on buried-food and habituationdishabituation tasks. The current studies describe an expanded method for using STFP in mice and confirm a deficit in olfactory memory in GAL-tg mice.

Original languageEnglish (US)
Pages (from-to)21-31
Number of pages11
JournalBehavioral Neuroscience
Volume117
Issue number1
DOIs
StatePublished - Feb 2003
Externally publishedYes

Fingerprint

Galanin
Food Preferences
Transgenic Mice
Interpersonal Relations
Aptitude
Smell
Research Design
Food

ASJC Scopus subject areas

  • Behavioral Neuroscience
  • Clinical Psychology

Cite this

Social transmission of food preference in mice : Methodology and application to galanin-overexpressing transgenic mice. / Wrenn, Craige C.; Harris, Ashley P.; Saavedra, Maria C.; Crawley, Jacqueline.

In: Behavioral Neuroscience, Vol. 117, No. 1, 02.2003, p. 21-31.

Research output: Contribution to journalArticle

@article{9ebc13463b0144a5baa324aa87884702,
title = "Social transmission of food preference in mice: Methodology and application to galanin-overexpressing transgenic mice",
abstract = "Social transmission of food preference (STFP) is a test of olfactory memory that can be used in mice. Confounds in STFP that can lead to misinterpretation of an STFP deficit as a memory impairment include changes in social interaction and olfaction. The issue of changes in social interaction was addressed by evaluating an observer-centric and a demonstrator-centric method for scoring the interaction phase of STFP in mice. The demonstrator-centric method was applied to a line of STFP-impaired, galaninoverexpressing transgenic (GAL-tg). GAL-tg mice were impaired in STFP without deficits in social interaction. In tests of olfactory ability, GAL-tg mice were unimpaired on buried-food and habituationdishabituation tasks. The current studies describe an expanded method for using STFP in mice and confirm a deficit in olfactory memory in GAL-tg mice.",
author = "Wrenn, {Craige C.} and Harris, {Ashley P.} and Saavedra, {Maria C.} and Jacqueline Crawley",
year = "2003",
month = "2",
doi = "10.1037/0735-7044.117.1.21",
language = "English (US)",
volume = "117",
pages = "21--31",
journal = "Behavioral Neuroscience",
issn = "0735-7044",
publisher = "American Psychological Association Inc.",
number = "1",

}

TY - JOUR

T1 - Social transmission of food preference in mice

T2 - Methodology and application to galanin-overexpressing transgenic mice

AU - Wrenn, Craige C.

AU - Harris, Ashley P.

AU - Saavedra, Maria C.

AU - Crawley, Jacqueline

PY - 2003/2

Y1 - 2003/2

N2 - Social transmission of food preference (STFP) is a test of olfactory memory that can be used in mice. Confounds in STFP that can lead to misinterpretation of an STFP deficit as a memory impairment include changes in social interaction and olfaction. The issue of changes in social interaction was addressed by evaluating an observer-centric and a demonstrator-centric method for scoring the interaction phase of STFP in mice. The demonstrator-centric method was applied to a line of STFP-impaired, galaninoverexpressing transgenic (GAL-tg). GAL-tg mice were impaired in STFP without deficits in social interaction. In tests of olfactory ability, GAL-tg mice were unimpaired on buried-food and habituationdishabituation tasks. The current studies describe an expanded method for using STFP in mice and confirm a deficit in olfactory memory in GAL-tg mice.

AB - Social transmission of food preference (STFP) is a test of olfactory memory that can be used in mice. Confounds in STFP that can lead to misinterpretation of an STFP deficit as a memory impairment include changes in social interaction and olfaction. The issue of changes in social interaction was addressed by evaluating an observer-centric and a demonstrator-centric method for scoring the interaction phase of STFP in mice. The demonstrator-centric method was applied to a line of STFP-impaired, galaninoverexpressing transgenic (GAL-tg). GAL-tg mice were impaired in STFP without deficits in social interaction. In tests of olfactory ability, GAL-tg mice were unimpaired on buried-food and habituationdishabituation tasks. The current studies describe an expanded method for using STFP in mice and confirm a deficit in olfactory memory in GAL-tg mice.

UR - http://www.scopus.com/inward/record.url?scp=0037311762&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0037311762&partnerID=8YFLogxK

U2 - 10.1037/0735-7044.117.1.21

DO - 10.1037/0735-7044.117.1.21

M3 - Article

C2 - 12619904

AN - SCOPUS:0037311762

VL - 117

SP - 21

EP - 31

JO - Behavioral Neuroscience

JF - Behavioral Neuroscience

SN - 0735-7044

IS - 1

ER -