Social cognition skills among females with fragile X

Michèle M M Mazzocco, Bruce F. Pennington, Randi J Hagerman

Research output: Contribution to journalArticle

41 Citations (Scopus)

Abstract

Emotion perception and perspective-taking skills were examined among women with or without the fragile X gene. The performance of 56 control women was compared to the performance of 46 women who were carriers of the fragile X gene. Twenty-seven of the carrier women had 0-1% cytogenetic expression and did not appear affected by the gene, whereas the remaining 19 women had ≥2% cytogenetic expression and did appear affected by the gene. The emotion perception task employed was one for which deficits have been reported among individuals with autism. The results show that performance on this emotion-perception test and the perspective-taking measure was significantly related to full-scale IQ scores, but not to fragile X group status when effects of IQ were removed. Thus the results do not support the hypothesis that perspective-taking or emotion perception deficits are a component of the fragile X phenotype in females and represent an important differentiation between fragile X and autism.

Original languageEnglish (US)
Pages (from-to)473-485
Number of pages13
JournalJournal of Autism and Developmental Disorders
Volume24
Issue number4
DOIs
StatePublished - Aug 1994
Externally publishedYes

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Cognition
Emotions
Autistic Disorder
Cytogenetics
Genes
Social Skills
Phenotype

ASJC Scopus subject areas

  • Developmental and Educational Psychology
  • Psychology(all)

Cite this

Social cognition skills among females with fragile X. / Mazzocco, Michèle M M; Pennington, Bruce F.; Hagerman, Randi J.

In: Journal of Autism and Developmental Disorders, Vol. 24, No. 4, 08.1994, p. 473-485.

Research output: Contribution to journalArticle

Mazzocco, Michèle M M ; Pennington, Bruce F. ; Hagerman, Randi J. / Social cognition skills among females with fragile X. In: Journal of Autism and Developmental Disorders. 1994 ; Vol. 24, No. 4. pp. 473-485.
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