Snake spectacle vessel permeability to sodium fluorescein

Roy W. Bellhorn, Ann R. Strom, Monica J. Motta, John Doval, Michelle Hawkins, Joanne R Paul-Murphy

Research output: Contribution to journalArticle

Abstract

Objective: Assess vascular permeability of the snake spectacle to sodium fluorescein during resting and shedding phases of the ecdysis cycle. Animal studied: Ball python (Python regius). Procedures: The snake was anesthetized, and spectral domain optic coherence tomography was performed prior to angiographic procedures. An electronically controlled digital single-lens reflex camera with a dual-head flash equipped with filters suitable for fluorescein angiography was used to make images. Sodium fluorescein (10%) solution was administered by intracardiac injection. Angiographic images were made as fluorescein traversed the vasculature of the iris and spectacle. Individually acquired photographic frames were assessed and sequenced into pseudovideo image streams for further evaluation Conclusions: Fluorescein angiograms of the snake spectacle were readily obtained. Vascular permeability varied with the phase of ecdysis. Copious leakage of fluorescein occurred during the shedding phase. This angiographic method may provide diverse opportunities to investigate vascular aspects of snake spectacle ecdysis, dysecdysis, and the integument in general.

Original languageEnglish (US)
JournalVeterinary Ophthalmology
DOIs
StateAccepted/In press - 2017

Fingerprint

Snakes
fluorescein
Fluorescein
snakes
Permeability
permeability
Molting
sodium
ecdysis
Boidae
blood vessels
Capillary Permeability
Fluorescein Angiography
Python
Iris
tomography
Lenses
Blood Vessels
Reflex
optics

Keywords

  • Ball python
  • Ecdysis
  • Fluorescein angiography
  • Permeability
  • Python regius
  • Snake spectacle

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Snake spectacle vessel permeability to sodium fluorescein. / Bellhorn, Roy W.; Strom, Ann R.; Motta, Monica J.; Doval, John; Hawkins, Michelle; Paul-Murphy, Joanne R.

In: Veterinary Ophthalmology, 2017.

Research output: Contribution to journalArticle

@article{a41d7687667c4aed85b4bb3f3e8d564a,
title = "Snake spectacle vessel permeability to sodium fluorescein",
abstract = "Objective: Assess vascular permeability of the snake spectacle to sodium fluorescein during resting and shedding phases of the ecdysis cycle. Animal studied: Ball python (Python regius). Procedures: The snake was anesthetized, and spectral domain optic coherence tomography was performed prior to angiographic procedures. An electronically controlled digital single-lens reflex camera with a dual-head flash equipped with filters suitable for fluorescein angiography was used to make images. Sodium fluorescein (10{\%}) solution was administered by intracardiac injection. Angiographic images were made as fluorescein traversed the vasculature of the iris and spectacle. Individually acquired photographic frames were assessed and sequenced into pseudovideo image streams for further evaluation Conclusions: Fluorescein angiograms of the snake spectacle were readily obtained. Vascular permeability varied with the phase of ecdysis. Copious leakage of fluorescein occurred during the shedding phase. This angiographic method may provide diverse opportunities to investigate vascular aspects of snake spectacle ecdysis, dysecdysis, and the integument in general.",
keywords = "Ball python, Ecdysis, Fluorescein angiography, Permeability, Python regius, Snake spectacle",
author = "Bellhorn, {Roy W.} and Strom, {Ann R.} and Motta, {Monica J.} and John Doval and Michelle Hawkins and Paul-Murphy, {Joanne R}",
year = "2017",
doi = "10.1111/vop.12483",
language = "English (US)",
journal = "Veterinary Ophthalmology",
issn = "1463-5216",
publisher = "Wiley-Blackwell",

}

TY - JOUR

T1 - Snake spectacle vessel permeability to sodium fluorescein

AU - Bellhorn, Roy W.

AU - Strom, Ann R.

AU - Motta, Monica J.

AU - Doval, John

AU - Hawkins, Michelle

AU - Paul-Murphy, Joanne R

PY - 2017

Y1 - 2017

N2 - Objective: Assess vascular permeability of the snake spectacle to sodium fluorescein during resting and shedding phases of the ecdysis cycle. Animal studied: Ball python (Python regius). Procedures: The snake was anesthetized, and spectral domain optic coherence tomography was performed prior to angiographic procedures. An electronically controlled digital single-lens reflex camera with a dual-head flash equipped with filters suitable for fluorescein angiography was used to make images. Sodium fluorescein (10%) solution was administered by intracardiac injection. Angiographic images were made as fluorescein traversed the vasculature of the iris and spectacle. Individually acquired photographic frames were assessed and sequenced into pseudovideo image streams for further evaluation Conclusions: Fluorescein angiograms of the snake spectacle were readily obtained. Vascular permeability varied with the phase of ecdysis. Copious leakage of fluorescein occurred during the shedding phase. This angiographic method may provide diverse opportunities to investigate vascular aspects of snake spectacle ecdysis, dysecdysis, and the integument in general.

AB - Objective: Assess vascular permeability of the snake spectacle to sodium fluorescein during resting and shedding phases of the ecdysis cycle. Animal studied: Ball python (Python regius). Procedures: The snake was anesthetized, and spectral domain optic coherence tomography was performed prior to angiographic procedures. An electronically controlled digital single-lens reflex camera with a dual-head flash equipped with filters suitable for fluorescein angiography was used to make images. Sodium fluorescein (10%) solution was administered by intracardiac injection. Angiographic images were made as fluorescein traversed the vasculature of the iris and spectacle. Individually acquired photographic frames were assessed and sequenced into pseudovideo image streams for further evaluation Conclusions: Fluorescein angiograms of the snake spectacle were readily obtained. Vascular permeability varied with the phase of ecdysis. Copious leakage of fluorescein occurred during the shedding phase. This angiographic method may provide diverse opportunities to investigate vascular aspects of snake spectacle ecdysis, dysecdysis, and the integument in general.

KW - Ball python

KW - Ecdysis

KW - Fluorescein angiography

KW - Permeability

KW - Python regius

KW - Snake spectacle

UR - http://www.scopus.com/inward/record.url?scp=85021242255&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85021242255&partnerID=8YFLogxK

U2 - 10.1111/vop.12483

DO - 10.1111/vop.12483

M3 - Article

C2 - 28635138

AN - SCOPUS:85021242255

JO - Veterinary Ophthalmology

JF - Veterinary Ophthalmology

SN - 1463-5216

ER -