Smaller left hemisphere planum temporale in adults with autistic disorder

Donald C. Rojas, Susie D. Bawn, Tara L. Benkers, Martin L. Reite, Sally J Rogers

Research output: Contribution to journalArticle

118 Citations (Scopus)

Abstract

The structure of the planum temporale is often disturbed in disorders with associated communication problems, particularly in auditory and language processing areas in the brain. We hypothesized that people with autism would have reduced left hemisphere volumes in the planum temporale, a language related brain structure. We performed magnetic resonance imaging scans of 15 adults with autistic disorder and 15 comparison subjects, and measured the volume of gray matter in the planum temporale and Heschl's gyrus (HG) in both hemispheres. Planum temporale volume reduced in the left hemisphere of the autism group (P<0.003). No differences in HG volumes were observed between the two groups. The volume reduction seen in the left hemisphere of the autism group may suggest an early neurodevelopmental disturbance in autism that impacts language development.

Original languageEnglish (US)
Pages (from-to)237-240
Number of pages4
JournalNeuroscience Letters
Volume328
Issue number3
DOIs
StatePublished - Aug 16 2002
Externally publishedYes

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Temazepam
Autistic Disorder
Auditory Cortex
Language
Language Development
Brain
Communication
Magnetic Resonance Imaging

Keywords

  • Cerebral asymmetry
  • Developmental disorder
  • Language
  • Magnetic resonance imaging
  • Mental retardation
  • Temporal lobe

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Smaller left hemisphere planum temporale in adults with autistic disorder. / Rojas, Donald C.; Bawn, Susie D.; Benkers, Tara L.; Reite, Martin L.; Rogers, Sally J.

In: Neuroscience Letters, Vol. 328, No. 3, 16.08.2002, p. 237-240.

Research output: Contribution to journalArticle

Rojas, Donald C. ; Bawn, Susie D. ; Benkers, Tara L. ; Reite, Martin L. ; Rogers, Sally J. / Smaller left hemisphere planum temporale in adults with autistic disorder. In: Neuroscience Letters. 2002 ; Vol. 328, No. 3. pp. 237-240.
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