Small molecules can have big effects on endurance

Keith Baar, D. Grahame Hardie

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Adaptation of muscle to endurance exercise training involves the coordinated expression of genes involved in oxidative metabolism, resulting in increased endurance. A recent study shows that small-molecule activators of two pathways thought to transduce these effects can enhance the effects of training, or even substitute for it.

Original languageEnglish (US)
Pages (from-to)583-584
Number of pages2
JournalNature Chemical Biology
Issue number10
StatePublished - Oct 2008
Externally publishedYes

ASJC Scopus subject areas

  • Cell Biology
  • Molecular Biology


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