Small molecules can have big effects on endurance

Keith Baar; D. Grahame Hardie

doi:10.1038/nchembio1008-583

Small molecules can have big effects on endurance

Keith Baar, D. Grahame Hardie

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Adaptation of muscle to endurance exercise training involves the coordinated expression of genes involved in oxidative metabolism, resulting in increased endurance. A recent study shows that small-molecule activators of two pathways thought to transduce these effects can enhance the effects of training, or even substitute for it.

Original language	English (US)
Pages (from-to)	583-584
Number of pages	2
Journal	Nature Chemical Biology
Volume	4
Issue number	10
DOIs	https://doi.org/10.1038/nchembio1008-583
State	Published - Oct 2008
Externally published	Yes

ASJC Scopus subject areas

Cell Biology
Molecular Biology

Access to Document

10.1038/nchembio1008-583

Fingerprint Dive into the research topics of 'Small molecules can have big effects on endurance'. Together they form a unique fingerprint.

Cite this

@article{14c5c2510a1e490e915fcdb8f9ef57fe,

title = "Small molecules can have big effects on endurance",

abstract = "Adaptation of muscle to endurance exercise training involves the coordinated expression of genes involved in oxidative metabolism, resulting in increased endurance. A recent study shows that small-molecule activators of two pathways thought to transduce these effects can enhance the effects of training, or even substitute for it.",

author = "Keith Baar and Hardie, {D. Grahame}",

year = "2008",

month = oct,

doi = "10.1038/nchembio1008-583",

language = "English (US)",

volume = "4",

pages = "583--584",

journal = "Nature Chemical Biology",

issn = "1552-4450",

publisher = "Nature Publishing Group",

number = "10",

}

TY - JOUR

T1 - Small molecules can have big effects on endurance

AU - Baar, Keith

AU - Hardie, D. Grahame

PY - 2008/10

Y1 - 2008/10

N2 - Adaptation of muscle to endurance exercise training involves the coordinated expression of genes involved in oxidative metabolism, resulting in increased endurance. A recent study shows that small-molecule activators of two pathways thought to transduce these effects can enhance the effects of training, or even substitute for it.

AB - Adaptation of muscle to endurance exercise training involves the coordinated expression of genes involved in oxidative metabolism, resulting in increased endurance. A recent study shows that small-molecule activators of two pathways thought to transduce these effects can enhance the effects of training, or even substitute for it.

UR - http://www.scopus.com/inward/record.url?scp=51949110481&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=51949110481&partnerID=8YFLogxK

U2 - 10.1038/nchembio1008-583

DO - 10.1038/nchembio1008-583

M3 - Article

C2 - 18800044

AN - SCOPUS:51949110481

VL - 4

SP - 583

EP - 584

JO - Nature Chemical Biology

JF - Nature Chemical Biology

SN - 1552-4450

IS - 10

ER -