Abstract
Objective: Report the results using porcine small intestinal submucosa (SIS) as a graft material in the surgical management of Peyronie's disease (PD). Materials and Methods: We performed a retrospective chart review of men with PD who underwent surgical correction of the curvature by plaque "H" incision and patch grafting with 4-ply SIS (Cook, Bloomington, IN) by a single surgeon at our institution. Degree and direction of curvature, sexual function, and co-morbidities were assessed pre- and postoperatively. Results: Thirteen patients were identified. Mean age was 57 ± 8, range 42-70 years. Median follow-up was 14 months, range 3-89 months. At presentation, all reported penile curvature. Also reported were difficulty with vaginal penetration (determined by question number 2 of the sexual encounter profile questionnaire - SEP2), palpable plaque, hourglass deformity, difficulty with firmness, and difficulty with sustaining erection (determined by SEP3) in77%, 69%, 77%, 62%, and 46% of patients, respectively. Mean and median degrees of curvature of the primary deformity were 71 and 67.5 degrees, respectively. Three patients had secondary curves of less than 30 degrees in a different direction. Mean and median plaque size were 3.5 and 2.7 cm2, respectively. Seven patients had one graft and six patients had two grafts placed with a mean size of 15 ± 0 cm2. Conclusions: For the patient with PD, SIS grafting can achieve a functionally straight erection with durable results yet with relatively high rates of erectile dysfunction. SIS is a viable graft material for use in the surgical treatment of PD.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 191-196 |
| Number of pages | 6 |
| Journal | International Braz J Urol |
| Volume | 34 |
| Issue number | 2 |
| State | Published - Mar 2008 |
| Externally published | Yes |
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Keywords
- Graft
- Penis
- Peyronie's disease
- Small intestinal submucosa
- Surgery
ASJC Scopus subject areas
- Nephrology
Cite this
Small intestinal submucosa for patch grafting after plaque incision in the treatment of Peyronie's disease. / Lee, Eugene W.; Shindel, Alan W; Brandes, Steven B.
In: International Braz J Urol, Vol. 34, No. 2, 03.2008, p. 191-196.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Small intestinal submucosa for patch grafting after plaque incision in the treatment of Peyronie's disease
AU - Lee, Eugene W.
AU - Shindel, Alan W
AU - Brandes, Steven B.
PY - 2008/3
Y1 - 2008/3
N2 - Objective: Report the results using porcine small intestinal submucosa (SIS) as a graft material in the surgical management of Peyronie's disease (PD). Materials and Methods: We performed a retrospective chart review of men with PD who underwent surgical correction of the curvature by plaque "H" incision and patch grafting with 4-ply SIS (Cook, Bloomington, IN) by a single surgeon at our institution. Degree and direction of curvature, sexual function, and co-morbidities were assessed pre- and postoperatively. Results: Thirteen patients were identified. Mean age was 57 ± 8, range 42-70 years. Median follow-up was 14 months, range 3-89 months. At presentation, all reported penile curvature. Also reported were difficulty with vaginal penetration (determined by question number 2 of the sexual encounter profile questionnaire - SEP2), palpable plaque, hourglass deformity, difficulty with firmness, and difficulty with sustaining erection (determined by SEP3) in77%, 69%, 77%, 62%, and 46% of patients, respectively. Mean and median degrees of curvature of the primary deformity were 71 and 67.5 degrees, respectively. Three patients had secondary curves of less than 30 degrees in a different direction. Mean and median plaque size were 3.5 and 2.7 cm2, respectively. Seven patients had one graft and six patients had two grafts placed with a mean size of 15 ± 0 cm2. Conclusions: For the patient with PD, SIS grafting can achieve a functionally straight erection with durable results yet with relatively high rates of erectile dysfunction. SIS is a viable graft material for use in the surgical treatment of PD.
AB - Objective: Report the results using porcine small intestinal submucosa (SIS) as a graft material in the surgical management of Peyronie's disease (PD). Materials and Methods: We performed a retrospective chart review of men with PD who underwent surgical correction of the curvature by plaque "H" incision and patch grafting with 4-ply SIS (Cook, Bloomington, IN) by a single surgeon at our institution. Degree and direction of curvature, sexual function, and co-morbidities were assessed pre- and postoperatively. Results: Thirteen patients were identified. Mean age was 57 ± 8, range 42-70 years. Median follow-up was 14 months, range 3-89 months. At presentation, all reported penile curvature. Also reported were difficulty with vaginal penetration (determined by question number 2 of the sexual encounter profile questionnaire - SEP2), palpable plaque, hourglass deformity, difficulty with firmness, and difficulty with sustaining erection (determined by SEP3) in77%, 69%, 77%, 62%, and 46% of patients, respectively. Mean and median degrees of curvature of the primary deformity were 71 and 67.5 degrees, respectively. Three patients had secondary curves of less than 30 degrees in a different direction. Mean and median plaque size were 3.5 and 2.7 cm2, respectively. Seven patients had one graft and six patients had two grafts placed with a mean size of 15 ± 0 cm2. Conclusions: For the patient with PD, SIS grafting can achieve a functionally straight erection with durable results yet with relatively high rates of erectile dysfunction. SIS is a viable graft material for use in the surgical treatment of PD.
KW - Graft
KW - Penis
KW - Peyronie's disease
KW - Small intestinal submucosa
KW - Surgery
UR - http://www.scopus.com/inward/record.url?scp=44449154709&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=44449154709&partnerID=8YFLogxK
M3 - Article
C2 - 18462517
AN - SCOPUS:44449154709
VL - 34
SP - 191
EP - 196
JO - International braz j urol : official journal of the Brazilian Society of Urology
JF - International braz j urol : official journal of the Brazilian Society of Urology
SN - 1677-5538
IS - 2
ER -