Abstract
This chapter describes PET systems for imaging of small animals. It also discusses the opportunities for bringing together high-resolution PET imaging systems with the techniques of modern molecular biology, functional genomics, and drug development. Important factors considered in the design of dedicated small animal PET scanners are identified and the geometry and performance of several first-generation systems are reviewed. This chapter also describes newer small animal PET systems that are under development. Last section illustrates some of the early applications of PET for studying small laboratory animals and identifies the challenges, opportunities, and ultimate limitations in applying PET to small animal imaging. The role of PET in modern biology has yet to be defined, but, if some of the challenges identified in this chapter can be overcome, then it is likely to play a significant role in the study of animal models of disease.
| Original language | English (US) |
|---|---|
| Title of host publication | Emission Tomography: The Fundamentals of PET and SPECT |
| Publisher | Elsevier Inc. |
| Pages | 213-228 |
| Number of pages | 16 |
| ISBN (Print) | 9780080521879, 9780127444826 |
| DOIs | |
| State | Published - Nov 18 2004 |
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ASJC Scopus subject areas
- Medicine(all)
- Neuroscience(all)
Cite this
Small Animal PET Systems. / Cherry, Simon R; Chatziioannou, Arion F.
Emission Tomography: The Fundamentals of PET and SPECT. Elsevier Inc., 2004. p. 213-228.Research output: Chapter in Book/Report/Conference proceeding › Chapter
}
TY - CHAP
T1 - Small Animal PET Systems
AU - Cherry, Simon R
AU - Chatziioannou, Arion F.
PY - 2004/11/18
Y1 - 2004/11/18
N2 - This chapter describes PET systems for imaging of small animals. It also discusses the opportunities for bringing together high-resolution PET imaging systems with the techniques of modern molecular biology, functional genomics, and drug development. Important factors considered in the design of dedicated small animal PET scanners are identified and the geometry and performance of several first-generation systems are reviewed. This chapter also describes newer small animal PET systems that are under development. Last section illustrates some of the early applications of PET for studying small laboratory animals and identifies the challenges, opportunities, and ultimate limitations in applying PET to small animal imaging. The role of PET in modern biology has yet to be defined, but, if some of the challenges identified in this chapter can be overcome, then it is likely to play a significant role in the study of animal models of disease.
AB - This chapter describes PET systems for imaging of small animals. It also discusses the opportunities for bringing together high-resolution PET imaging systems with the techniques of modern molecular biology, functional genomics, and drug development. Important factors considered in the design of dedicated small animal PET scanners are identified and the geometry and performance of several first-generation systems are reviewed. This chapter also describes newer small animal PET systems that are under development. Last section illustrates some of the early applications of PET for studying small laboratory animals and identifies the challenges, opportunities, and ultimate limitations in applying PET to small animal imaging. The role of PET in modern biology has yet to be defined, but, if some of the challenges identified in this chapter can be overcome, then it is likely to play a significant role in the study of animal models of disease.
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UR - http://www.scopus.com/inward/citedby.url?scp=33745225210&partnerID=8YFLogxK
U2 - 10.1016/B978-012744482-6.50015-6
DO - 10.1016/B978-012744482-6.50015-6
M3 - Chapter
AN - SCOPUS:33745225210
SN - 9780080521879
SN - 9780127444826
SP - 213
EP - 228
BT - Emission Tomography: The Fundamentals of PET and SPECT
PB - Elsevier Inc.
ER -