Sliding filaments and mitotic spindle organization

Haifeng Wang, Ingrid Brust-Mascher, Jonathan M. Scholey

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


Mitosis depends upon the action of the mitotic spindle, a subcellular machine that uses microtubules (MTs) and motors to assemble itself and to coordinate chromosome segregation. Recent work illuminates how the motor-driven poleward sliding of MTs-nucleated at centrosomes, chromosomes and on pre-existing MTs-contributes to spindle assembly and length control.

Original languageEnglish (US)
Pages (from-to)737-739
Number of pages3
JournalNature Cell Biology
Issue number8
StatePublished - 2014

ASJC Scopus subject areas

  • Cell Biology
  • Medicine(all)


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