Sleep disorders in patients with multiple sclerosis

Steven D. Brass, Pierre Duquette, Joëlle Proulx-Therrien, Sanford Auerbach

Research output: Contribution to journalArticlepeer-review

112 Scopus citations


Patients with multiple sclerosis (MS) often have unrecognized sleep disorders at higher frequency than the general population. Sleep disorders such as sleep disordered breathing, insomnia, REM sleep behavior disorder, narcolepsy and restless legs syndrome have all been reported in the MS population. Notably, the most common symptom of MS is "fatigue," which itself has been correlated with sleep disturbances. Sleep disorders may impact the quality of life of the MS patient population. This paper reviews the association of sleep disorders with MS, and discusses the association of sleep disruption with MS fatigue.

Original languageEnglish (US)
Pages (from-to)121-129
Number of pages9
JournalSleep Medicine Reviews
Issue number2
StatePublished - Apr 2010


  • Excessive daytime sleepiness
  • Fatigue
  • Insomnia
  • Multiple sclerosis
  • Obstructive sleep apnea syndrome
  • Restless legs syndrome
  • Sleep

ASJC Scopus subject areas

  • Clinical Neurology
  • Physiology (medical)
  • Pulmonary and Respiratory Medicine
  • Neurology


Dive into the research topics of 'Sleep disorders in patients with multiple sclerosis'. Together they form a unique fingerprint.

Cite this