Skull base tumors: Surgical considerations

Francisco Vaz-Guimaraes, Griffith R. Harsh

Research output: Chapter in Book/Report/Conference proceedingChapter


Surgical resection is considered the mainstay treatment modality of most skull base chordomas and chondrosarcomas. Adequate exposure for maximal safe tumor resection while reducing the risks of complications and properly reconstructing the skull base defect created during the approach are the fundamental principles of skull base surgery. Nevertheless, the choice of surgical approach to these tumors requires a thorough understanding of the anatomy of the central skull base from which they most commonly arise. This chapter will review important considerations in the management of patients harboring skull base chordomas and chondrosarcomas with emphasis on surgical treatment and will include a comprehensive description of open transcranial and endoscopic endonasal approaches, which should ultimately assist the reader in selecting the most appropriate surgical approach and treatment strategy for individual patients.

Original languageEnglish (US)
Title of host publicationChordomas and Chondrosarcomas of the Skull Base and Spine
PublisherElsevier Inc.
Number of pages23
ISBN (Electronic)9780128043332
ISBN (Print)9780128042571
StatePublished - 2018
Externally publishedYes


  • Chondrosarcomas
  • Chordomas
  • Endoscopic endonasal approaches
  • Microsurgical resection
  • Preoperative planning
  • Skull base anatomy
  • Skull base approaches
  • Skull base tumors
  • Surgical corridors
  • Transcranial approaches

ASJC Scopus subject areas

  • Medicine(all)
  • Neuroscience(all)


Dive into the research topics of 'Skull base tumors: Surgical considerations'. Together they form a unique fingerprint.

Cite this