Skeletal lesions of histiocytic sarcoma in nineteen dogs

Ryan M. Schultz, Sarah M. Puchalski, Michael S Kent, Peter F Moore

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

The purpose of this study was to describe the clinical and radiographic findings in dogs with bone lesions secondary to histiocytic sarcoma. Nineteen dogs with radiographically identified bone lesions that were histologically diagnosed as histiocytic sarcoma were assessed. The medical records, all available radiographs and histologic sections were reviewed retrospectively. Dogs were subcategorized into localized or disseminated histiocytic sarcoma groups. Golden Retrievers or Rottweilers greater than 5 years of age, with a history of lameness or neurologic deficits localized to the spinal cord was the most common presentation. Fifteen of 19 dogs had a radiographically detectable soft tissue mass associated with bone destruction. The bone lesions had aggressive characteristics and the sites of involvement included periarticular bones (n=11), vertebrae (n=6), proximal humerus (n=5), and rib (n=2). Fifteen of 19 dogs had disseminated histiocytic sarcoma, and four had localized histiocytic sarcoma. All Rottweilers had disseminated histiocytic sarcoma. Histiocytic sarcoma should be considered as a differential diagnosis for aggressive periarticular, vertebral, or proximal humeral bone lesions identified on radiographs. The index of suspicion should be increased in greater than 5-year-old Golden Retrievers and Rottweilers when a soft tissue mass is associated with the bone lesion on radiographs or myelography. Bone involvement with histiocytic sarcoma, and the Rottweiler breed, was associated with the disseminated form of the disease.

Original languageEnglish (US)
Pages (from-to)539-543
Number of pages5
JournalVeterinary Radiology and Ultrasound
Volume48
Issue number6
DOIs
StatePublished - Nov 2007

Fingerprint

Histiocytic Sarcoma
sarcoma
lesions (animal)
bones
Dogs
Rottweiler
Bone and Bones
dogs
Golden Retriever
Myelography
humerus
Humerus
Ribs
Neurologic Manifestations
vertebrae
ribs
nervous system
spinal cord
lameness
Medical Records

Keywords

  • Bone
  • Canine
  • Histiocytic sarcoma
  • Malignant histiocytosis
  • Radiograph

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Skeletal lesions of histiocytic sarcoma in nineteen dogs. / Schultz, Ryan M.; Puchalski, Sarah M.; Kent, Michael S; Moore, Peter F.

In: Veterinary Radiology and Ultrasound, Vol. 48, No. 6, 11.2007, p. 539-543.

Research output: Contribution to journalArticle

Schultz, Ryan M. ; Puchalski, Sarah M. ; Kent, Michael S ; Moore, Peter F. / Skeletal lesions of histiocytic sarcoma in nineteen dogs. In: Veterinary Radiology and Ultrasound. 2007 ; Vol. 48, No. 6. pp. 539-543.
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