Sjögren syndrome complicated by mucosa-associated lymphoid tissue lymphoma and lymphocytic interstitial pneumonia

Fatma Ahmed, Osama Raslan, Razi Muzaffar, Nadeem Parkar, Nitin Marwaha, Medhat M. Osman

Research output: Contribution to journalArticle


Sjögren syndrome (SS) is an autoimmune disease with exocrine glands dysfunction and multiorgan involvement. It is associated with increased risk of lymphoproliferative disorders, especially B-cell marginal zone lymphoma. While the role of F-18 Fluorodeoxyglucose position emission tomography/computed tomography (F-18 FDG PET/CT) for evaluation of lymphoma has been established, its use in patients with a chronic history of SS to evaluate for possible lymphoproliferative disorders or multiorgan involvement is limited. We present a case of chronic SS in which F-18 FDG PET/CT demonstrated FDG avid intraparotid and cervical lymph nodes pathologically proven to be mucosa-associated lymphoid tissue lymphoma. In addition, the patient had bibasilar cystic changes consistent with lymphocytic interstitial pneumonia.

Original languageEnglish (US)
Article number179
JournalFrontiers in Oncology
Issue numberAug
StatePublished - Jan 1 2015
Externally publishedYes



  • FDG avid
  • LIP
  • MALT lymphoma
  • Sjögren syndrome

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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