SIV of stump-tailed macaque (SIVstm) is a divergent Asian isolate.

A. S. Khan; T. A. Galvin; M. B. Jennings; M. B. Gardner; Linda J Lowenstine

SIV of stump-tailed macaque (SIVstm) is a divergent Asian isolate.

A. S. Khan, T. A. Galvin, M. B. Jennings, M. B. Gardner, Linda J Lowenstine

Research output: Contribution to journal › Article › peer-review

Abstract

Analysis of molecularly cloned DNAs of SIVs isolated from Asian rhesus macaque (Macaca mulatta; SIVmac) and pig-tailed macaque (Macaca nemestrina; SIVmne) has indicated a high degree of sequence homology between these viruses. Thus SIVmac and SIVmne might have originated from the same or very closely related viruses. We have cloned and sequenced a PCR-amplified segment containing the LTR sequences of SIV originating from a stump-tailed macaque (Macaca arctoides; SIVstm). Comparative sequence analysis indicates that SIVstm belongs to the SIV/HIV-2 group; however, it is genetically distinct from the other members.

Original language	English (US)
Pages (from-to)	167-171
Number of pages	5
Journal	Journal of Medical Primatology
Volume	20
Issue number	4
State	Published - Jun 1991
Externally published	Yes

ASJC Scopus subject areas

Animal Science and Zoology
veterinary(all)

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title = "SIV of stump-tailed macaque (SIVstm) is a divergent Asian isolate.",

abstract = "Analysis of molecularly cloned DNAs of SIVs isolated from Asian rhesus macaque (Macaca mulatta; SIVmac) and pig-tailed macaque (Macaca nemestrina; SIVmne) has indicated a high degree of sequence homology between these viruses. Thus SIVmac and SIVmne might have originated from the same or very closely related viruses. We have cloned and sequenced a PCR-amplified segment containing the LTR sequences of SIV originating from a stump-tailed macaque (Macaca arctoides; SIVstm). Comparative sequence analysis indicates that SIVstm belongs to the SIV/HIV-2 group; however, it is genetically distinct from the other members.",

author = "Khan, {A. S.} and Galvin, {T. A.} and Jennings, {M. B.} and Gardner, {M. B.} and Lowenstine, {Linda J}",

year = "1991",

month = jun,

language = "English (US)",

volume = "20",

pages = "167--171",

journal = "Journal of Medical Primatology",

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T1 - SIV of stump-tailed macaque (SIVstm) is a divergent Asian isolate.

AU - Khan, A. S.

AU - Galvin, T. A.

AU - Jennings, M. B.

AU - Gardner, M. B.

AU - Lowenstine, Linda J

PY - 1991/6

Y1 - 1991/6

N2 - Analysis of molecularly cloned DNAs of SIVs isolated from Asian rhesus macaque (Macaca mulatta; SIVmac) and pig-tailed macaque (Macaca nemestrina; SIVmne) has indicated a high degree of sequence homology between these viruses. Thus SIVmac and SIVmne might have originated from the same or very closely related viruses. We have cloned and sequenced a PCR-amplified segment containing the LTR sequences of SIV originating from a stump-tailed macaque (Macaca arctoides; SIVstm). Comparative sequence analysis indicates that SIVstm belongs to the SIV/HIV-2 group; however, it is genetically distinct from the other members.

AB - Analysis of molecularly cloned DNAs of SIVs isolated from Asian rhesus macaque (Macaca mulatta; SIVmac) and pig-tailed macaque (Macaca nemestrina; SIVmne) has indicated a high degree of sequence homology between these viruses. Thus SIVmac and SIVmne might have originated from the same or very closely related viruses. We have cloned and sequenced a PCR-amplified segment containing the LTR sequences of SIV originating from a stump-tailed macaque (Macaca arctoides; SIVstm). Comparative sequence analysis indicates that SIVstm belongs to the SIV/HIV-2 group; however, it is genetically distinct from the other members.

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SIV of stump-tailed macaque (SIVstm) is a divergent Asian isolate.

Abstract

ASJC Scopus subject areas

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