TY - JOUR
T1 - Sites of age-related sensitivity loss in a short-wave cone pathway.
AU - Schefrin, B. E.
AU - Werner, John S
AU - Plach, M.
AU - Utlaut, N.
AU - Switkes, E.
PY - 1992/3
Y1 - 1992/3
N2 - The age-related losses in the sensitivity of a short-wave (S) cone mechanism were determined by measuring the threshold-versus-radiance (t.v.r.) functions for nine older (mean age, 71.0 years) and six younger (mean age, 24.4 years) subjects. Measurements were obtained for a 250-ms, 1.03 degrees-diameter, 440-nm foveally viewed test light presented on 470-nm adapting fields and on a 570-nm auxiliary field. A comparison of t.v.r. functions revealed intensity-dependent sensitivity losses in the older group. By applying a quantitative model of an S-cone pathway to the t.v.r. data obtained from the older subjects, we found that the age-related changes in the ocular media and the receptor sensitivities can account for much but not all of the difference in the sensitivity of an S-cone mechanism demonstrated by eight of our nine older subjects.
AB - The age-related losses in the sensitivity of a short-wave (S) cone mechanism were determined by measuring the threshold-versus-radiance (t.v.r.) functions for nine older (mean age, 71.0 years) and six younger (mean age, 24.4 years) subjects. Measurements were obtained for a 250-ms, 1.03 degrees-diameter, 440-nm foveally viewed test light presented on 470-nm adapting fields and on a 570-nm auxiliary field. A comparison of t.v.r. functions revealed intensity-dependent sensitivity losses in the older group. By applying a quantitative model of an S-cone pathway to the t.v.r. data obtained from the older subjects, we found that the age-related changes in the ocular media and the receptor sensitivities can account for much but not all of the difference in the sensitivity of an S-cone mechanism demonstrated by eight of our nine older subjects.
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M3 - Article
C2 - 1548554
AN - SCOPUS:0026832324
VL - 9
SP - 355
EP - 363
JO - Journal of the Optical Society of America. A, Optics and image science
JF - Journal of the Optical Society of America. A, Optics and image science
SN - 1084-7529
IS - 3
ER -