When calfskin collagen is treated with trichloroaceti c acid at 90°C, it is hydrolyzed to a mixture of pep-tides, some of which are quite small. Cleavage of collagen by acid seems to occur at bonds between pro-line (or hydroxyproline) and other amino acids, with only a limited specificity for which amino acid donates its amino group to the susceptible peptide bond.
ASJC Scopus subject areas
- Cell Biology
- Molecular Biology
- Orthopedics and Sports Medicine