TY - JOUR
T1 - Single-strand conformational polymorphism (SSCP) mapping of the mouse genome
T2 - Integration of the SSCP, microsatellite, and gene maps of mouse chromosome 1
AU - Hunter, K. W.
AU - Watson, M. L.
AU - Rochelle, J.
AU - Ontiveros, S.
AU - Munroe, D.
AU - Seldin, Michael F
AU - Housman, D. E.
PY - 1993
Y1 - 1993
N2 - Interspersed repetitive sequence (IRS) PCR and repetitive element-to- bubble (IRS-bubble) PCR have been utilized to rapidly generate large numbers of mouse-specific, chromosome 1-enriched STSs from mouse-hamster somatic cell hybrids. Single-strand conformational polymorphism (SSCP) has been used to localize 39 new repetitive element-linked STSs to the mouse map: 22 to Chr 1, 10 to Chr. 15, 2 each to Chrs 12 and 14, and three to Chr 7. In addition, we have integrated the SSCP, single-strand length polymorphism, and restriction fragment length polymorphism maps of mouse Chr. 1, resulting in a high- density map of the chromosome, containing over 100 loci, all typed on a single interspecific backcross.
AB - Interspersed repetitive sequence (IRS) PCR and repetitive element-to- bubble (IRS-bubble) PCR have been utilized to rapidly generate large numbers of mouse-specific, chromosome 1-enriched STSs from mouse-hamster somatic cell hybrids. Single-strand conformational polymorphism (SSCP) has been used to localize 39 new repetitive element-linked STSs to the mouse map: 22 to Chr 1, 10 to Chr. 15, 2 each to Chrs 12 and 14, and three to Chr 7. In addition, we have integrated the SSCP, single-strand length polymorphism, and restriction fragment length polymorphism maps of mouse Chr. 1, resulting in a high- density map of the chromosome, containing over 100 loci, all typed on a single interspecific backcross.
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M3 - Article
C2 - 8307560
AN - SCOPUS:0027770696
VL - 18
SP - 510
EP - 519
JO - Genomics
JF - Genomics
SN - 0888-7543
IS - 3
ER -