Single fiber electromyography of extraocular muscles: A sensitive method for the diagnosis of ocular myasthenia gravis

A. Rivero; L. Crovetto; L. Lopez; Ricardo A Maselli; M. Nogues

doi:10.1002/mus.880180904

Single fiber electromyography of extraocular muscles: A sensitive method for the diagnosis of ocular myasthenia gravis

A. Rivero, L. Crovetto, L. Lopez, Ricardo A Maselli, M. Nogues

Neurology

Research output: Contribution to journal › Article

41 Scopus citations

Abstract

We performed single fiber electromyography (SFEMG) in the superior rectus and levator palpebralis (SR-LP) muscles of 17 patients with pure ocular myasthenia gravis (MG) and 9 controls. Thirteen patients were also assessed with SFEMG in the orbicularis oculi (OO) muscle. All the MG patients but none of the control subjects showed abnormal SFEMG jitter in the SR-LP muscles. On the other hand, only 62% of the MG patients had abnormal SFEMG jitter in the OO muscle. The procedure was well tolerated by the patients, and complications were minor. We conclude that SFEMG of the SR-LP muscles is a safe and highly sensitive technique for the diagnosis of ocular MG.

Original language	English (US)
Pages (from-to)	943-947
Number of pages	5
Journal	Muscle and Nerve
Volume	18
Issue number	9
DOIs	https://doi.org/10.1002/mus.880180904
State	Published - 1995

Fingerprint

Keywords

ocular MG
ophthalmoparesis
single fiber electromyography
SR-LP muscles

ASJC Scopus subject areas

Clinical Neurology
Neuroscience(all)

Cite this

Rivero, A., Crovetto, L., Lopez, L., Maselli, R. A., & Nogues, M. (1995). Single fiber electromyography of extraocular muscles: A sensitive method for the diagnosis of ocular myasthenia gravis. Muscle and Nerve, 18(9), 943-947. https://doi.org/10.1002/mus.880180904

@article{8d3fed092bd6454db88cf219c86d6481,

title = "Single fiber electromyography of extraocular muscles: A sensitive method for the diagnosis of ocular myasthenia gravis",

abstract = "We performed single fiber electromyography (SFEMG) in the superior rectus and levator palpebralis (SR-LP) muscles of 17 patients with pure ocular myasthenia gravis (MG) and 9 controls. Thirteen patients were also assessed with SFEMG in the orbicularis oculi (OO) muscle. All the MG patients but none of the control subjects showed abnormal SFEMG jitter in the SR-LP muscles. On the other hand, only 62% of the MG patients had abnormal SFEMG jitter in the OO muscle. The procedure was well tolerated by the patients, and complications were minor. We conclude that SFEMG of the SR-LP muscles is a safe and highly sensitive technique for the diagnosis of ocular MG.",

keywords = "ocular MG, ophthalmoparesis, single fiber electromyography, SR-LP muscles",

author = "A. Rivero and L. Crovetto and L. Lopez and Maselli, {Ricardo A} and M. Nogues",

year = "1995",

doi = "10.1002/mus.880180904",

language = "English (US)",

volume = "18",

pages = "943--947",

journal = "Muscle and Nerve",

issn = "0148-639X",

publisher = "John Wiley and Sons Inc.",

number = "9",

}

TY - JOUR

T1 - Single fiber electromyography of extraocular muscles

T2 - A sensitive method for the diagnosis of ocular myasthenia gravis

AU - Rivero, A.

AU - Crovetto, L.

AU - Lopez, L.

AU - Maselli, Ricardo A

AU - Nogues, M.

PY - 1995

Y1 - 1995

N2 - We performed single fiber electromyography (SFEMG) in the superior rectus and levator palpebralis (SR-LP) muscles of 17 patients with pure ocular myasthenia gravis (MG) and 9 controls. Thirteen patients were also assessed with SFEMG in the orbicularis oculi (OO) muscle. All the MG patients but none of the control subjects showed abnormal SFEMG jitter in the SR-LP muscles. On the other hand, only 62% of the MG patients had abnormal SFEMG jitter in the OO muscle. The procedure was well tolerated by the patients, and complications were minor. We conclude that SFEMG of the SR-LP muscles is a safe and highly sensitive technique for the diagnosis of ocular MG.

AB - We performed single fiber electromyography (SFEMG) in the superior rectus and levator palpebralis (SR-LP) muscles of 17 patients with pure ocular myasthenia gravis (MG) and 9 controls. Thirteen patients were also assessed with SFEMG in the orbicularis oculi (OO) muscle. All the MG patients but none of the control subjects showed abnormal SFEMG jitter in the SR-LP muscles. On the other hand, only 62% of the MG patients had abnormal SFEMG jitter in the OO muscle. The procedure was well tolerated by the patients, and complications were minor. We conclude that SFEMG of the SR-LP muscles is a safe and highly sensitive technique for the diagnosis of ocular MG.

KW - ocular MG

KW - ophthalmoparesis

KW - single fiber electromyography

KW - SR-LP muscles

UR - http://www.scopus.com/inward/record.url?scp=0029131955&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0029131955&partnerID=8YFLogxK

U2 - 10.1002/mus.880180904

DO - 10.1002/mus.880180904

M3 - Article

C2 - 7643873

AN - SCOPUS:0029131955

VL - 18

SP - 943

EP - 947

JO - Muscle and Nerve

JF - Muscle and Nerve

SN - 0148-639X

IS - 9

ER -

Access to Document

10.1002/mus.880180904