Simulation study for designing a compact brain PET scanner

Kuang Gong, Stan Majewski, Paul E. Kinahan, Robert L. Harrison, Brian F. Elston, Ravindra Manjeshwar, Sergei Dolinsky, Alexander V. Stolin, Julie A. Brefczynski-Lewis, Jinyi Qi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations

Abstract

The desire to understand normal and disordered human brain of upright, moving persons in natural environments motivates the development of an ambulatory micro-dose brain PET imager (AMPET) [1]. An ideal system would be light weight and have high sensitivity and spatial resolution. These requirements are often in conflict with each other. Therefore, we performed simulation studies to search for the optimal system configuration and to evaluate the improvement in performance over existing scanners. An intuitive design to achieve high sensitivity is to use a tight geometry that covers the brain. However, a tight geometry also increases parallax error in peripheral lines of response, which may increase the variance in ROI quantification.

Original languageEnglish (US)
Title of host publication2015 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2015
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)9781467398626
DOIs
StatePublished - Oct 3 2016
Event2015 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2015 - San Diego, United States
Duration: Oct 31 2015Nov 7 2015

Other

Other2015 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2015
CountryUnited States
CitySan Diego
Period10/31/1511/7/15

ASJC Scopus subject areas

  • Nuclear and High Energy Physics
  • Radiology Nuclear Medicine and imaging
  • Instrumentation

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    Gong, K., Majewski, S., Kinahan, P. E., Harrison, R. L., Elston, B. F., Manjeshwar, R., Dolinsky, S., Stolin, A. V., Brefczynski-Lewis, J. A., & Qi, J. (2016). Simulation study for designing a compact brain PET scanner. In 2015 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2015 [7582245] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/NSSMIC.2015.7582245