Simulation of the thermoregulatory system of rats exposed concurrently to cold and to acceleration fields

A CSMP model has been developed that describes the thermoregulatory response of cold-exposed rats to acceleration fields of 1 to 5g. Experiments were designed to determine the temporal period over which the model accounts for responses of animals to concurrent cold and gravitational stressors. During the first hour following the onset of hypergravity, the model is not applicable since it includes no factors for regulation of peripheral blood flow. However, one hour after the onset of hypergravity, the model is appropriate since the thermoregulatory response that occurs is via graded control of shivering and nonshivering thermogenesis.