Simple adaptive mobile phone screen illumination for dual phone differential phase contrast (DPDPC) microscopy

Sara Kheireddine, Zachary J. Smith, Dan V. Nicolau, Sebastian Wachsmann-Hogiu

Research output: Contribution to journalArticle

Abstract

Phase contrast imaging is widely employed in the physical, biological, and medical sciences. However, typical implementations involve complex imaging systems that amount to in-line interferometers. We adapt differential phase contrast (DPC) to a dual-phone illumination-imaging system to obtain phase contrast images on a portable mobile phone platform. In this dual phone differential phase contrast (dpDPC) microscope, semicircles are projected sequentially on the display of one phone, and images are captured using a low-cost, short focal length lens attached to the second phone. By numerically combining images obtained using these semicircle patterns, high quality DPC images with ≈ 2 micrometer resolution can be easily acquired with no specialized hardware, circuitry, or instrument control programs.

Original languageEnglish (US)
Pages (from-to)4369-4380
Number of pages12
JournalBiomedical Optics Express
Volume10
Issue number9
DOIs
StatePublished - Sep 1 2019

ASJC Scopus subject areas

  • Biotechnology
  • Atomic and Molecular Physics, and Optics

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