Abstract
Prior studies that included both adult and pediatric recipients suggested slower early graft function for laparoscopically (vs. openly) procured live donor kidney grafts (LD-Ktxs). Any potential long-term impact, however, remains unknown. We compared long-term outcomes of 2685 (49%) laparoscopic vs. 2847 (51%) open LD-Ktxs reported to the Organ Procurement and Transplantation Network performed in adult (≥18 yrs) recipients between November 1999 and December 2000, with follow-up to February 2006. Acute and chronic rejection accounted for 152 laparoscopic (51%) vs. 148 (46%) open graft losses (P=NS). At discharge and at 5 years, graft function was similar for both groups; graft survival at 5 years was 79% (laparoscopic) vs. 80% (open) (P=NS). We conclude that despite prior reports of slower early laparoscopic LD-Ktx function, both laparoscopic and open nephrectomy are equally effective for procurement of kidneys for adult recipients with regard to short- and long-term (>5 years) function and survival. Future studies must investigate whether these findings apply also to pediatric LD-Ktx recipients.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 916-919 |
| Number of pages | 4 |
| Journal | Transplantation |
| Volume | 85 |
| Issue number | 6 |
| DOIs | |
| State | Published - Mar 2008 |
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Keywords
- Kidney graft survival
- Kidney recipient outcome
- Kidney transplantation
- Laparoscopic nephrectomy
- Live kidney donor
- Surgical technique
ASJC Scopus subject areas
- Transplantation
- Immunology
Cite this
Similar long-term outcomes for laparoscopic versus open live-donor nephrectomy kidney grafts : An OPTN database analysis of 5532 adult recipients. / Troppmann, Christoph; Perez, Richard V; McBride, Maureen.
In: Transplantation, Vol. 85, No. 6, 03.2008, p. 916-919.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Similar long-term outcomes for laparoscopic versus open live-donor nephrectomy kidney grafts
T2 - An OPTN database analysis of 5532 adult recipients
AU - Troppmann, Christoph
AU - Perez, Richard V
AU - McBride, Maureen
PY - 2008/3
Y1 - 2008/3
N2 - Prior studies that included both adult and pediatric recipients suggested slower early graft function for laparoscopically (vs. openly) procured live donor kidney grafts (LD-Ktxs). Any potential long-term impact, however, remains unknown. We compared long-term outcomes of 2685 (49%) laparoscopic vs. 2847 (51%) open LD-Ktxs reported to the Organ Procurement and Transplantation Network performed in adult (≥18 yrs) recipients between November 1999 and December 2000, with follow-up to February 2006. Acute and chronic rejection accounted for 152 laparoscopic (51%) vs. 148 (46%) open graft losses (P=NS). At discharge and at 5 years, graft function was similar for both groups; graft survival at 5 years was 79% (laparoscopic) vs. 80% (open) (P=NS). We conclude that despite prior reports of slower early laparoscopic LD-Ktx function, both laparoscopic and open nephrectomy are equally effective for procurement of kidneys for adult recipients with regard to short- and long-term (>5 years) function and survival. Future studies must investigate whether these findings apply also to pediatric LD-Ktx recipients.
AB - Prior studies that included both adult and pediatric recipients suggested slower early graft function for laparoscopically (vs. openly) procured live donor kidney grafts (LD-Ktxs). Any potential long-term impact, however, remains unknown. We compared long-term outcomes of 2685 (49%) laparoscopic vs. 2847 (51%) open LD-Ktxs reported to the Organ Procurement and Transplantation Network performed in adult (≥18 yrs) recipients between November 1999 and December 2000, with follow-up to February 2006. Acute and chronic rejection accounted for 152 laparoscopic (51%) vs. 148 (46%) open graft losses (P=NS). At discharge and at 5 years, graft function was similar for both groups; graft survival at 5 years was 79% (laparoscopic) vs. 80% (open) (P=NS). We conclude that despite prior reports of slower early laparoscopic LD-Ktx function, both laparoscopic and open nephrectomy are equally effective for procurement of kidneys for adult recipients with regard to short- and long-term (>5 years) function and survival. Future studies must investigate whether these findings apply also to pediatric LD-Ktx recipients.
KW - Kidney graft survival
KW - Kidney recipient outcome
KW - Kidney transplantation
KW - Laparoscopic nephrectomy
KW - Live kidney donor
KW - Surgical technique
UR - http://www.scopus.com/inward/record.url?scp=41149134502&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=41149134502&partnerID=8YFLogxK
U2 - 10.1097/TP.0b013e318166ad77
DO - 10.1097/TP.0b013e318166ad77
M3 - Article
C2 - 18360277
AN - SCOPUS:41149134502
VL - 85
SP - 916
EP - 919
JO - Transplantation
JF - Transplantation
SN - 0041-1337
IS - 6
ER -