SILCS diaphragm: postcoital testing of a new single-size contraceptive device

Jill L. Schwartz, Susan A. Ballagh, Mitchell D Creinin, Robert W. Rountree, Maggie Kilbourne-Brook, Christine K. Mauck, Marianne M. Callahan

Research output: Contribution to journalArticle

37 Scopus citations

Abstract

Background: This study was conducted to compare the effectiveness of a new, single-size silicone contraceptive diaphragm used with either spermicide [2% nonoxynol-9 (N-9)] or lubricant in preventing sperm from penetrating midcycle cervical mucus. Study design: A crossover postcoital test (PCT) in healthy, sexually active women not at risk for pregnancy due to tubal occlusion was conducted. Couples had a baseline PCT without a device to verify normal fertility parameters. Qualified couples underwent up to two test cycles using the SILCS diaphragm with a metal spring. A subgroup of couples underwent a third test cycle with the SILCS polymer spring diaphragm used with N-9 gel. Results: Fifteen couples completed a baseline cycle and were randomized to order of study gel. Of these, 14 couples completed a baseline cycle and at least one test cycle, 12 couples completed a baseline cycle and two test cycles and 8 couples completed a third test cycle with the polymer spring prototype. Sperm was detected in the vaginal pool in all completed test cycles. The SILCS metal spring diaphragms used with N-9 gel reduced the average number of progressively motile sperm per high power field in the cervical mucus from a baseline of 12.5 to 0, while use of this device with lubricant reduced the number to 0.5. The SILCS polymer spring diaphragm used with N-9 performed the same as the metal spring used with N-9. Conclusion: The SILCS diaphragm used with N-9 gel performed well. It is likely that the SILCS diaphragm will give acceptable results in a contraceptive effectiveness study but that adjunctive use of a chemical barrier such as N-9 gel will be necessary for it to be most effective.

Original languageEnglish (US)
Pages (from-to)237-244
Number of pages8
JournalContraception
Volume78
Issue number3
DOIs
StatePublished - Sep 2008
Externally publishedYes

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Keywords

  • Diaphragm
  • Nonoxynol-9
  • Postcoital test
  • SILCS

ASJC Scopus subject areas

  • Medicine(all)
  • Obstetrics and Gynecology

Cite this

Schwartz, J. L., Ballagh, S. A., Creinin, M. D., Rountree, R. W., Kilbourne-Brook, M., Mauck, C. K., & Callahan, M. M. (2008). SILCS diaphragm: postcoital testing of a new single-size contraceptive device. Contraception, 78(3), 237-244. https://doi.org/10.1016/j.contraception.2008.04.118