Significance of autogenously regulated and constitutive synthesis of regulatory proteins in repressible biosynthetic systems

Michael A. Savageau

Research output: Contribution to journalArticlepeer-review

22 Scopus citations

Abstract

The functional implications of the different modes of regulation have been examined systematically. The results lead to certain predictions. The regulatory protein in repressor-controlled systems is constitutively synthesised. In activator-controlled systems synthesis of the regulatory protein is autogenously regulated. There is favourable agreement between these predictions and published experimental evidence.

Original languageEnglish (US)
Pages (from-to)208-214
Number of pages7
JournalNature
Volume258
Issue number5532
DOIs
StatePublished - 1975
Externally publishedYes

ASJC Scopus subject areas

  • General

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