Significance of autogenously regulated and constitutive synthesis of regulatory proteins in repressible biosynthetic systems

Michael A. Savageau

Research output: Contribution to journalArticle

21 Scopus citations

Abstract

The functional implications of the different modes of regulation have been examined systematically. The results lead to certain predictions. The regulatory protein in repressor-controlled systems is constitutively synthesised. In activator-controlled systems synthesis of the regulatory protein is autogenously regulated. There is favourable agreement between these predictions and published experimental evidence.

Original languageEnglish (US)
Pages (from-to)208-214
Number of pages7
JournalNature
Volume258
Issue number5532
DOIs
StatePublished - 1975
Externally publishedYes

ASJC Scopus subject areas

  • General

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