Abstract
Antigenic epitopes on the major core (gag) protein of isolates of simian and human immunodeficiency virus (SIV and HIV) were compared using a panel of eleven mouse monoclonal antibodies (Mabs) that recognized nine distinct gag epitopes. Viral isolates used for comparison were HIV-1IIIb, HIV-2ROD, and SIV isolates from macaque (SIVmac), sooty mangabey (SIVsm-UCD), African green monkey (SIVagm), and stump-tailed macaque (SIVstm-UCD). The relatedness of the various HIV and SIV isolates, as determined by Mabs to core protein epitopes, paralleled that ascertained by genetic sequencing.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 265-269 |
| Number of pages | 5 |
| Journal | Journal of Medical Primatology |
| Volume | 21 |
| Issue number | 5 |
| State | Published - Jul 1992 |
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ASJC Scopus subject areas
- Animal Science and Zoology
- veterinary(all)
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Shared antigenic epitopes of the major core proteins of human and simian immunodeficiency virus isolates. / Higgins, J. R.; Sutjipto, S.; Marx, P. A.; Pedersen, Niels C.
In: Journal of Medical Primatology, Vol. 21, No. 5, 07.1992, p. 265-269.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Shared antigenic epitopes of the major core proteins of human and simian immunodeficiency virus isolates.
AU - Higgins, J. R.
AU - Sutjipto, S.
AU - Marx, P. A.
AU - Pedersen, Niels C
PY - 1992/7
Y1 - 1992/7
N2 - Antigenic epitopes on the major core (gag) protein of isolates of simian and human immunodeficiency virus (SIV and HIV) were compared using a panel of eleven mouse monoclonal antibodies (Mabs) that recognized nine distinct gag epitopes. Viral isolates used for comparison were HIV-1IIIb, HIV-2ROD, and SIV isolates from macaque (SIVmac), sooty mangabey (SIVsm-UCD), African green monkey (SIVagm), and stump-tailed macaque (SIVstm-UCD). The relatedness of the various HIV and SIV isolates, as determined by Mabs to core protein epitopes, paralleled that ascertained by genetic sequencing.
AB - Antigenic epitopes on the major core (gag) protein of isolates of simian and human immunodeficiency virus (SIV and HIV) were compared using a panel of eleven mouse monoclonal antibodies (Mabs) that recognized nine distinct gag epitopes. Viral isolates used for comparison were HIV-1IIIb, HIV-2ROD, and SIV isolates from macaque (SIVmac), sooty mangabey (SIVsm-UCD), African green monkey (SIVagm), and stump-tailed macaque (SIVstm-UCD). The relatedness of the various HIV and SIV isolates, as determined by Mabs to core protein epitopes, paralleled that ascertained by genetic sequencing.
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UR - http://www.scopus.com/inward/citedby.url?scp=0026885882&partnerID=8YFLogxK
M3 - Article
C2 - 1383547
AN - SCOPUS:0026885882
VL - 21
SP - 265
EP - 269
JO - Journal of Medical Primatology
JF - Journal of Medical Primatology
SN - 0047-2565
IS - 5
ER -