Abstract
Antigenic epitopes on the major core (gag) protein of isolates of simian and human immunodeficiency virus (SIV and HIV) were compared using a panel of eleven mouse monoclonal antibodies (Mabs) that recognized nine distinct gag epitopes. Viral isolates used for comparison were HIV-1IIIb, HIV-2ROD, and SIV isolates from macaque (SIVmac), sooty mangabey (SIVsm-UCD), African green monkey (SIVagm), and stump-tailed macaque (SIVstm-UCD). The relatedness of the various HIV and SIV isolates, as determined by Mabs to core protein epitopes, paralleled that ascertained by genetic sequencing.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 265-269 |
| Number of pages | 5 |
| Journal | Journal of Medical Primatology |
| Volume | 21 |
| Issue number | 5 |
| State | Published - Jul 1992 |
ASJC Scopus subject areas
- Animal Science and Zoology
- veterinary(all)
Fingerprint Dive into the research topics of 'Shared antigenic epitopes of the major core proteins of human and simian immunodeficiency virus isolates.'. Together they form a unique fingerprint.
Cite this
Higgins, J. R., Sutjipto, S., Marx, P. A., & Pedersen, N. C. (1992). Shared antigenic epitopes of the major core proteins of human and simian immunodeficiency virus isolates. Journal of Medical Primatology, 21(5), 265-269.