Abstract
Antigenic epitopes on the major core (gag) protein of isolates of simian and human immunodeficiency virus (SIV and HIV) were compared using a panel of eleven mouse monoclonal antibodies (Mabs) that recognized nine distinct gag epitopes. Viral isolates used for comparison were HIV-1IIIb, HIV-2ROD, and SIV isolates from macaque (SIVmac), sooty mangabey (SIVsm-UCD), African green monkey (SIVagm), and stump-tailed macaque (SIVstm-UCD). The relatedness of the various HIV and SIV isolates, as determined by Mabs to core protein epitopes, paralleled that ascertained by genetic sequencing.
Original language | English (US) |
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Pages (from-to) | 265-269 |
Number of pages | 5 |
Journal | Journal of Medical Primatology |
Volume | 21 |
Issue number | 5 |
State | Published - Jul 1992 |
ASJC Scopus subject areas
- Animal Science and Zoology
- veterinary(all)