Severe rhabdomyolysis with renal failure after intranasal cocaine use

B. Zane Horowitz, Edward A Panacek, Nicholas J. Jouriles

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

A case of acute renal failure due to rhabdomyolysis in a patient who used cocaine on a daily basis is presented. In contrast to many prior reports of renal failure occurring with cocaine-associated rhabdomyolysis, our patient did not use intravenous cocaine and did not have any evidence of trauma, seizure, hypotension, hyperthermia, hyperactivity, or coma. His creatine phosphokinase peaked at 448,000 U/liter. He was treated initially with forced diuresis and i.v. furosemide, but he became oliguric, developed pulmonary edema, and required hemodialysis. He recovered fully after 3 weeks of dialysis. The literature is reviewed in an attempt to delineate a rational approach to evaluating cocaine users at risk for rhabdomyolysis.

Original languageEnglish (US)
Pages (from-to)833-837
Number of pages5
JournalJournal of Emergency Medicine
Volume15
Issue number6
DOIs
StatePublished - Nov 1997

Fingerprint

Rhabdomyolysis
Cocaine
Renal Insufficiency
Diuresis
Furosemide
Pulmonary Edema
Creatine Kinase
Coma
Acute Kidney Injury
Hypotension
Renal Dialysis
Dialysis
Seizures
Fever
Wounds and Injuries

Keywords

  • Cocaine
  • Creatinine kinase
  • Myoglobin
  • Renal failure
  • Rhabdomyolysis

ASJC Scopus subject areas

  • Emergency Medicine

Cite this

Severe rhabdomyolysis with renal failure after intranasal cocaine use. / Horowitz, B. Zane; Panacek, Edward A; Jouriles, Nicholas J.

In: Journal of Emergency Medicine, Vol. 15, No. 6, 11.1997, p. 833-837.

Research output: Contribution to journalArticle

Horowitz, B. Zane ; Panacek, Edward A ; Jouriles, Nicholas J. / Severe rhabdomyolysis with renal failure after intranasal cocaine use. In: Journal of Emergency Medicine. 1997 ; Vol. 15, No. 6. pp. 833-837.
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