Sesame seed food allergy

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

A food allergy is any adverse reaction to a food that is mediated by the immune system. The most well-known type of food allergy reactions are those that involve IgE antibody specifically directed to peptide epitopes, either conformational or sequential in nature, on proteins within an edible food. IgE antibodies bind to high affinity receptors on effector cells called mast cells (distributed in tissues, and especially rich in skin and mucosa) and basophils (found circulating in blood, but can egress into tissues). When two or more IgE antibodies are cross-linked, the mast cell or basophil is activated, resulting in release of preformed and newly formed chemical and peptide mediators, which may continue to amplify an allergic reaction (Figure 8.1 and Table 8.1). Histamine is the most well-known of these mediators, but cystinyl leukotrienes, cytokines, and chemokines that attract additional inflammatory cells to the site of a reaction are critically important as well, most easily seen on a practical level by the fact that while histamine receptor blockers (antihistamines) may block urticarial (hive) reactions, they do not stop anaphylaxis, which involves multiple mediators at multiple organ sites.

Original languageEnglish (US)
Title of host publicationSesame
Subtitle of host publicationThe Genus Sesamum
PublisherCRC Press
Pages155-168
Number of pages14
ISBN (Electronic)9781420005202
ISBN (Print)9780849335389
DOIs
StatePublished - Jan 1 2010

Fingerprint

Sesamum
Allergies
sesame seed
food allergies
Food Hypersensitivity
Immunoglobulin E
Seed
Seeds
basophils
Basophils
Antibodies
mast cells
histamine
Mast Cells
antibodies
peptides
Peptides
antihistamines
Histamine Receptors
Food

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Engineering(all)
  • Chemistry(all)

Cite this

Teuber, S. S. (2010). Sesame seed food allergy. In Sesame: The Genus Sesamum (pp. 155-168). CRC Press. https://doi.org/10.1201/b13601

Sesame seed food allergy. / Teuber, Suzanne S.

Sesame: The Genus Sesamum. CRC Press, 2010. p. 155-168.

Research output: Chapter in Book/Report/Conference proceedingChapter

Teuber, SS 2010, Sesame seed food allergy. in Sesame: The Genus Sesamum. CRC Press, pp. 155-168. https://doi.org/10.1201/b13601
Teuber SS. Sesame seed food allergy. In Sesame: The Genus Sesamum. CRC Press. 2010. p. 155-168 https://doi.org/10.1201/b13601
Teuber, Suzanne S. / Sesame seed food allergy. Sesame: The Genus Sesamum. CRC Press, 2010. pp. 155-168
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