In 56 patients in whom the glomerular filtration rate (GFR) was estimated by the 51Cr-EDTA technique, serum creatinine and B2-microglobulin levels were also measured. In the 15 patients with a GFR of ≥ 80 ml/min, both serum creatinine and B2-microglobulin levels were within the relerence range. However, the B2-microglobulin level was elevated (>2,3 mg/l) in all 41 patients with a GFR of < 80 ml/min, while the serum creatinine levels was increased (> 133 μmol/l) in only 35 patients. In the remaining 6 patients, the creatinine values ranged from 75 to 125 μmol/l. It would therefore seem that serum B2-microglobulin assay is a more sensitive test than creatinine assay for detecting impaired renal function.
|Original language||English (US)|
|Number of pages||2|
|Journal||South African Medical Journal|
|State||Published - 1982|
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