Abstract
In 56 patients in whom the glomerular filtration rate (GFR) was estimated by the 51Cr-EDTA technique, serum creatinine and B2-microglobulin levels were also measured. In the 15 patients with a GFR of ≥ 80 ml/min, both serum creatinine and B2-microglobulin levels were within the relerence range. However, the B2-microglobulin level was elevated (>2,3 mg/l) in all 41 patients with a GFR of < 80 ml/min, while the serum creatinine levels was increased (> 133 μmol/l) in only 35 patients. In the remaining 6 patients, the creatinine values ranged from 75 to 125 μmol/l. It would therefore seem that serum B2-microglobulin assay is a more sensitive test than creatinine assay for detecting impaired renal function.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 953-954 |
| Number of pages | 2 |
| Journal | South African Medical Journal |
| Volume | 61 |
| Issue number | 25 |
| State | Published - 1982 |
| Externally published | Yes |
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Serum beta-2-microglobulin estimation as an indicator of the glomerular filtration rate. / Jialal, I.; Nathoo, B. C.; Bejai, S.; Joubert, S. M.
In: South African Medical Journal, Vol. 61, No. 25, 1982, p. 953-954.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Serum beta-2-microglobulin estimation as an indicator of the glomerular filtration rate
AU - Jialal, I.
AU - Nathoo, B. C.
AU - Bejai, S.
AU - Joubert, S. M.
PY - 1982
Y1 - 1982
N2 - In 56 patients in whom the glomerular filtration rate (GFR) was estimated by the 51Cr-EDTA technique, serum creatinine and B2-microglobulin levels were also measured. In the 15 patients with a GFR of ≥ 80 ml/min, both serum creatinine and B2-microglobulin levels were within the relerence range. However, the B2-microglobulin level was elevated (>2,3 mg/l) in all 41 patients with a GFR of < 80 ml/min, while the serum creatinine levels was increased (> 133 μmol/l) in only 35 patients. In the remaining 6 patients, the creatinine values ranged from 75 to 125 μmol/l. It would therefore seem that serum B2-microglobulin assay is a more sensitive test than creatinine assay for detecting impaired renal function.
AB - In 56 patients in whom the glomerular filtration rate (GFR) was estimated by the 51Cr-EDTA technique, serum creatinine and B2-microglobulin levels were also measured. In the 15 patients with a GFR of ≥ 80 ml/min, both serum creatinine and B2-microglobulin levels were within the relerence range. However, the B2-microglobulin level was elevated (>2,3 mg/l) in all 41 patients with a GFR of < 80 ml/min, while the serum creatinine levels was increased (> 133 μmol/l) in only 35 patients. In the remaining 6 patients, the creatinine values ranged from 75 to 125 μmol/l. It would therefore seem that serum B2-microglobulin assay is a more sensitive test than creatinine assay for detecting impaired renal function.
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UR - http://www.scopus.com/inward/citedby.url?scp=0019989562&partnerID=8YFLogxK
M3 - Article
VL - 61
SP - 953
EP - 954
JO - South African Medical Journal
JF - South African Medical Journal
SN - 0038-2469
IS - 25
ER -