Serum (1→3)-β-D-glucan measurement in coccidioidomycosis

George Richard Thompson, Derek J. Bays, Suzanne M. Johnson, Stuart H Cohen, Demosthenes Pappagianis, Malcolm A. Finkelman

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

The serum (1→3)-β-D-glucan assay has emerged as an important diagnostic test for invasive fungal disease. The utility of this assay in coccidioidomycosis has not been previously studied. Using a cutoff value of ≥80 pg/ml, we found the sensitivity (43.9%), specificity (91.1%), positive predictive value (81.8%), and negative predictive value (64.1%) to be similar to those of the assay in diagnosing other invasive mycoses.

Original languageEnglish (US)
Pages (from-to)3060-3062
Number of pages3
JournalJournal of Clinical Microbiology
Volume50
Issue number9
DOIs
StatePublished - Sep 2012

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Coccidioidomycosis
Mycoses
Routine Diagnostic Tests
Sensitivity and Specificity
Serum
polyglucosan
Invasive Fungal Infections

ASJC Scopus subject areas

  • Microbiology (medical)

Cite this

Serum (1→3)-β-D-glucan measurement in coccidioidomycosis. / Thompson, George Richard; Bays, Derek J.; Johnson, Suzanne M.; Cohen, Stuart H; Pappagianis, Demosthenes; Finkelman, Malcolm A.

In: Journal of Clinical Microbiology, Vol. 50, No. 9, 09.2012, p. 3060-3062.

Research output: Contribution to journalArticle

Thompson, George Richard ; Bays, Derek J. ; Johnson, Suzanne M. ; Cohen, Stuart H ; Pappagianis, Demosthenes ; Finkelman, Malcolm A. / Serum (1→3)-β-D-glucan measurement in coccidioidomycosis. In: Journal of Clinical Microbiology. 2012 ; Vol. 50, No. 9. pp. 3060-3062.
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