Seroprevalence of Powassan virus in New England deer, 1979-2010

Robert A. Nofchissey, Eleanor R. Deardorff, Tia M. Blevins, Michael Anishchenko, Angela Bosco-Lauth, Erica Berl, Charles Lubelczyk, John Paul Mutebi, Aaron Brault, Gregory D. Ebel, Louis A. Magnarelli

Research output: Contribution to journalArticlepeer-review

19 Scopus citations

Abstract

Powassan virus and its subtype, deer tick virus, are closely related tick-borne flaviviruses that circulate in North America. The incidence of human infection by these agents appears to have increased in recent years. To define exposure patterns among white-tailed deer, potentially useful sentinels that are frequently parasitized by ticks, we screened serum samples collected during 1979 -2010 in Connecticut, Maine, and Vermont for neutralizing antibody by using a novel recombinant deer tick virus -West Nile virus chimeric virus. Evidence of exposure was detected in all three states. Overall our results demonstrate that seroprevalence is variable in time and space, suggesting that risk of exposure to Powassan virus is similarly variable.

Original languageEnglish (US)
Pages (from-to)1159-1162
Number of pages4
JournalAmerican Journal of Tropical Medicine and Hygiene
Volume88
Issue number6
DOIs
StatePublished - Jun 1 2013
Externally publishedYes

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases
  • Virology

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