Serological investigation of transplacental infection with Neospora hughesi and Sarcocystis neurona in broodmares

Nicola Pusterla, Sarah Mackie, Andrea Packham, Patricia A Conrad

Research output: Contribution to journalArticle

11 Scopus citations


The aim of the present study was to investigate the likelihood of transplacental transmission of Neospora hughesi and Sarcocystis neurona in foals, born from seropositive mares. Three broodmares with persistent N.-hughesi infection gave birth to eight healthy foals over a period of 7 years. These foals were seropositive to N.-hughesi prior to colostrum ingestion, with titers ranging between 640 and 20,480, measured by indirect fluorescence antibody test (IFAT). Of 174 foals born at another farm to mares with a high seroprevalence to S.-neurona, only one (with a pre-colostrum antibody titer of 80) tested seropositive. Transplacental transmission of N.-hughesi seems to occur from latently infected mares to their foals, while this route of transmission does not seem to occur commonly for S.-neurona.

Original languageEnglish (US)
Pages (from-to)649-650
Number of pages2
JournalVeterinary Journal
Issue number3
StatePublished - Dec 1 2014



  • Horse
  • Indirect fluorescence antibody test
  • Neospora hughesi
  • Sarcocystis neurona
  • Transplacental infection

ASJC Scopus subject areas

  • Animal Science and Zoology
  • veterinary(all)

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