Serial haematology results in transfused and non-transfused dogs naturally infected with Babesia rossi

E. Scheepers, A. L. Leisewitz, P. N. Thompson, Mary M Christopher

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

This prospective longitudinal study investigated the progression of haematological changes in 32 transfused and 54 non-transfused dogs naturally infected with Babesia rossi over the 1st 6 days following diagnosis and treatment. The effect of patient age on the results of complete blood counts was determined. Haematology data were analysed at presentation and at 24 hours, 3 days and 6 days after presentation. Dogs were treated with diminazene aceturate at diagnosis and a blood transfusion was given if deemed clinically required. Mildly to moderately regenerative normocytic normochromic anaemia was observed in all dogs throughout the study period. Transfused dogs more often had an inflammatory leukogram at presentation and at 24 hours, than dogs that were not transfused. In dogs with a left shift, a concurrent normal or decreased segmented neutrophil count was found more commonly than neutrophilia. Severe thrombocytopenia that resolved within a week was common. Blood transfusion alleviated the anaemia, but had no significant effect on white blood cell or platelet responses. Blood cell responses were not significantly influenced by age. In conclusion, the red blood cell and white blood cell responses were less than expected in dogs with babesiosis, given the degree of anaemia and inflammation present. The magnitude of thrombocytopenia and rapid return of the platelet count to normal suggested a possible immune-mediated mechanism for the thrombocytopenia.

Original languageEnglish (US)
Pages (from-to)136-143
Number of pages8
JournalJournal of the South African Veterinary Association
Volume82
Issue number3
StatePublished - Sep 2011

Fingerprint

Babesia
Hematology
hematology
Dogs
dogs
thrombocytopenia
Thrombocytopenia
anemia
Anemia
blood transfusion
Blood Transfusion
leukocytes
Leukocytes
diminazene
Babesiosis
blood platelets
Blood Cell Count
babesiosis
blood platelet count
longitudinal studies

Keywords

  • Anaemia
  • Babesia rossi
  • Canine babesiosis
  • Haematology
  • Left shift
  • Thrombocytopenia

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Serial haematology results in transfused and non-transfused dogs naturally infected with Babesia rossi. / Scheepers, E.; Leisewitz, A. L.; Thompson, P. N.; Christopher, Mary M.

In: Journal of the South African Veterinary Association, Vol. 82, No. 3, 09.2011, p. 136-143.

Research output: Contribution to journalArticle

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