Serial changes in blood pressure from adolescence into adulthood

Laurel A Beckett, Bernard Rosner, Alex F. Roche, Shumei Guo

Research output: Contribution to journalArticle

92 Scopus citations

Abstract

High blood pressure is an established risk factor for cardiovascular disease outcomes in adulthood. Furthermore, numerous longitudinal studies of blood pressure in childhood with length of follow-up from 1 to 17 years indicate that blood pressure levels track over the short term. This study addresses the question of the predictive value of childhood blood pressure readings for adult levels, using repeated blood pressure determinations from a sample of 501 participants in the Fels Longitudinal Study, and ongoing cohort study in southwestern Ohio that began in 1929. A damped autoregressive model indicated tracking correlations from 0.39 (4-year intervals) to 0.24 (20 years) for systolic pressure and 0.37 (4 years) to 0.20 (20 years) for diastolic pressure. These results indicate that tracking of blood pressure persists from age 13 years to age 40 years, which translates into moderate levels of relative risk for adult hypertension (diastolic pressure above 90 mmHg) for adolescents with high normal blood pressure. The estimated relative risks of hypertension at age 35 for white 15-years-olds with a true mean diastolic pressure of 80 mmHg were 1.9 for males and 2.6 for females, relative to 15-year-olds with a true diastolic pressure of 60 mmHg. Am J Epidemiol 1992: 135: 1166-77.

Original languageEnglish (US)
Pages (from-to)1166-1177
Number of pages12
JournalAmerican Journal of Epidemiology
Volume135
Issue number10
StatePublished - May 15 1992
Externally publishedYes

Keywords

  • Biometry
  • Blood pressure
  • Epidemiologic methods
  • Hypertension

ASJC Scopus subject areas

  • Geriatrics and Gerontology
  • Epidemiology

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