Abstract
The sequence of the coding region of the rRNA operon of rat-derived Pneumocystis carinii has been completed, including the genes for 5.8S and 26S rRNA. These genes show homology to the rRNA genes of yeast, and an apparent group I self-splicing intron is present in the 26S rRNA gene. Like a similar intron in the 16S rRNA gene, this intron is in a phylogenetically conserved region. Variation in the 26S rRNA sequence was noted between P.carinii organisms isolated from two different sources.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 3763-3772 |
| Number of pages | 10 |
| Journal | Nucleic Acids Research |
| Volume | 20 |
| Issue number | 14 |
| State | Published - Jul 25 1992 |
| Externally published | Yes |
ASJC Scopus subject areas
- Genetics
- Statistics, Probability and Uncertainty
- Applied Mathematics
- Health, Toxicology and Mutagenesis
- Toxicology
- Genetics(clinical)
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Cite this
Liu, Y., Rocourt, M., Pan, S., Liu, C., & Leibowitz, M. J. (1992). Sequence and variability of the 5.85 and 26S rRNA genes of Pneumocystis carinii. Nucleic Acids Research, 20(14), 3763-3772.