@article{88b72e5034684a959ca8e2af1da548b0,
title = "Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution",
abstract = "We present here a draft genome sequence of the red jungle fowl, Gallus gallus. Because the chicken is a modern descendant of the dinosaurs and the first non-mammalian amniote to have its genome sequenced, the draft sequence of its genome-composed of approximately one billion base pairs of sequence and an estimated 20,000-23,000 genes-provides a new perspective on vertebrate genome evolution, while also improving the annotation of mammalian genomes. For example, the evolutionary distance between chicken and human provides high specificity in detecting functional elements, both non-coding and coding. Notably, many conserved non-coding sequences are far from genes and cannot be assigned to defined functional classes. In coding regions the evolutionary dynamics of protein domains and orthologous groups illustrate processes that distinguish the lineages leading to birds and mammals. The distinctive properties of avian microchromosomes, together with the inferred patterns of conserved synteny, provide additional insights into vertebrate chromosome architecture.",
author = "{International Chicken Genome Sequencing Consortium} and Hillier, {Ladeana W.} and Webb Miller and Ewan Birney and Wesley Warren and Hardison, {Ross C.} and Ponting, {Chris P.} and Peer Bork and Burt, {David W.} and Groenen, {Martien A.M.} and Delany, {Mary E.} and Dodgson, {Jerry B.} and Chinwalla, {Asif T.} and Cliften, {Paul F.} and Clifton, {Sandra W.} and Delehaunty, {Kimberly D.} and Catrina Fronick and Fulton, {Robert S.} and Graves, {Tina A.} and Colin Kremitzki and Dan Layman and Vincent Magrini and McPherson, {John D.} and Miner, {Tracie L.} and Patrick Minx and Nash, {William E.} and Nhan, {Michael N.} and Nelson, {Joanne O.} and Oddy, {Lachlan G.} and Pohl, {Craig S.} and Jennifer Randall-Maher and Smith, {Scott M.} and Wallis, {John W.} and Yang, {Shiaw Pyng} and Romanov, {Michael N.} and Rondelli, {Catherine M.} and Bob Paton and Jacqueline Smith and David Morrice and Laura Daniels and Tempest, {Helen G.} and Lindsay Robertson and Masabanda, {Julio S.} and Griffin, {Darren K.} and Alain Vignal and Valerie Fillon and Lina Jacobbson and Susanne Kerje and Leif Andersson and Crooijmans, {Richard P.M.} and Jan Aerts",
year = "2004",
month = dec,
day = "9",
doi = "10.1038/nature03154",
language = "English (US)",
volume = "432",
pages = "695--716",
journal = "Nature",
issn = "0028-0836",
publisher = "Nature Publishing Group",
number = "7018",
}