TY - JOUR
T1 - Sequence analysis of the βB2-crystallin cDNA of hamster containing a domain conserved among vertebrates
AU - Zarbalis, Konstantinos
AU - Chatterjee, Bimal
AU - Löster, Jana
AU - Werner, Thomas
AU - Graw, Jochen
PY - 1996/9/26
Y1 - 1996/9/26
N2 - The cDNA sequence of the βB2-cry was determined from hamster (Mesocricetus auratus) and compared to the corresponding genes of bovine, frog, chicken, human, mouse and rat. Multispecies comparison demonstrated high homology between the hamster, rat and mouse gene, but larger distances to man, bovine, chicken and frog. There is striking identity within a strech of 36 deduced amino acids (aa) between the Greek key motif 3 and part of motif 4. This 36-aa domain contains a putative phosphorylation site for protein kinase C and is highly conserved among all known basic βB-Cry; however, it can neither be detected in the acidic βA- nor in the γ-Cry.
AB - The cDNA sequence of the βB2-cry was determined from hamster (Mesocricetus auratus) and compared to the corresponding genes of bovine, frog, chicken, human, mouse and rat. Multispecies comparison demonstrated high homology between the hamster, rat and mouse gene, but larger distances to man, bovine, chicken and frog. There is striking identity within a strech of 36 deduced amino acids (aa) between the Greek key motif 3 and part of motif 4. This 36-aa domain contains a putative phosphorylation site for protein kinase C and is highly conserved among all known basic βB-Cry; however, it can neither be detected in the acidic βA- nor in the γ-Cry.
KW - DNA sequence analysis
KW - Evolution
KW - Eye protein
KW - Polymerase chain reaction
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U2 - 10.1016/0378-1119(96)00256-9
DO - 10.1016/0378-1119(96)00256-9
M3 - Article
C2 - 8863746
AN - SCOPUS:0030603237
VL - 174
SP - 181
EP - 184
JO - Gene
JF - Gene
SN - 0378-1119
IS - 1
ER -