Sensitivity of a hand-held indentation probe for measuring the stiffness of articular cartilage

G. G. Niederauer, G. M. Niederauer, L. C. Cullen, K. A. Athanasiou, J. B. Thomas, M. Q. Niederauer

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The in vivo assessment of the quality of cartilage is a critical tool to determine how to clinically treat damaged cartilage. Utilizing non-destructive indentation, a hand-held instrument (ACTAEON™ Probe) can be used to rapidly measure the stiffness of articular cartilage, which can then be correlated to cartilage condition. The engineering design aspects of the instrument and the feasibility testing which have been undertaken using both animal and human knee joints are presented. An integrated series of tests were performed to determine whether the Probe is sensitive enough to detect early degenerative changes in articular cartilage and to examine if it is dependent on the thickness of the cartilage being tested. Results demonstrated that there is no effect of thickness on the Probe measurements, that the Probe is sensitive enough to detect different levels of cartilage degeneration, and that Probe data correlate well with traditional creep indentation testing. This study demonstrates the utility of the Probe for detecting degenerative changes in animal and human joints.

Original languageEnglish (US)
Title of host publicationAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Pages2591-2592
Number of pages2
Volume3
StatePublished - 2002
Externally publishedYes
EventProceedings of the 2002 IEEE Engineering in Medicine and Biology 24th Annual Conference and the 2002 Fall Meeting of the Biomedical Engineering Society (BMES / EMBS) - Houston, TX, United States
Duration: Oct 23 2002Oct 26 2002

Other

OtherProceedings of the 2002 IEEE Engineering in Medicine and Biology 24th Annual Conference and the 2002 Fall Meeting of the Biomedical Engineering Society (BMES / EMBS)
CountryUnited States
CityHouston, TX
Period10/23/0210/26/02

Fingerprint

Cartilage
Indentation
Stiffness
Animals
Testing
Creep

Keywords

  • Articular cartilage
  • Biomechanics
  • Indentation

ASJC Scopus subject areas

  • Bioengineering

Cite this

Niederauer, G. G., Niederauer, G. M., Cullen, L. C., Athanasiou, K. A., Thomas, J. B., & Niederauer, M. Q. (2002). Sensitivity of a hand-held indentation probe for measuring the stiffness of articular cartilage. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings (Vol. 3, pp. 2591-2592)

Sensitivity of a hand-held indentation probe for measuring the stiffness of articular cartilage. / Niederauer, G. G.; Niederauer, G. M.; Cullen, L. C.; Athanasiou, K. A.; Thomas, J. B.; Niederauer, M. Q.

Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. Vol. 3 2002. p. 2591-2592.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Niederauer, GG, Niederauer, GM, Cullen, LC, Athanasiou, KA, Thomas, JB & Niederauer, MQ 2002, Sensitivity of a hand-held indentation probe for measuring the stiffness of articular cartilage. in Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. vol. 3, pp. 2591-2592, Proceedings of the 2002 IEEE Engineering in Medicine and Biology 24th Annual Conference and the 2002 Fall Meeting of the Biomedical Engineering Society (BMES / EMBS), Houston, TX, United States, 10/23/02.
Niederauer GG, Niederauer GM, Cullen LC, Athanasiou KA, Thomas JB, Niederauer MQ. Sensitivity of a hand-held indentation probe for measuring the stiffness of articular cartilage. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. Vol. 3. 2002. p. 2591-2592
Niederauer, G. G. ; Niederauer, G. M. ; Cullen, L. C. ; Athanasiou, K. A. ; Thomas, J. B. ; Niederauer, M. Q. / Sensitivity of a hand-held indentation probe for measuring the stiffness of articular cartilage. Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. Vol. 3 2002. pp. 2591-2592
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